Graphicalized vision-language modeling for comprehensive lung nodule analysis and risk stratification

By: Danwen Zhao · Junfeng Xi · Xun Guo · Jintao Chai · Zhengshui Xu · Liang Li · Yan Xue · Qingyu Sun · Yinggang Zheng · Shiyuan Liu

11 April 2026 at 08:00

npj Digital Medicine, Published online: 11 April 2026; doi:10.1038/s41746-026-02602-9

Clinical application of base editing for treating β-thalassaemia

Nature - Issue - nature.com science feeds

By: Yongrong Lai · Rongrong Liu · Lijie Wang · Xu-Kai Ma · Yaliang Li · Gaohui Yang · Lingling Shi · Yi-Lin Guo · Zhenbin Wei · Xuemei Zhou · Wenchao Xu · Yaofeng Hou · Annarita Miccio · Bei Yang · Xiaodun Mou · Li Yang · Jia Chen

8 April 2026 at 08:00

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10342-9

A clinical phase 1 trial of a single infusion of CS-101, CD34+ cells modified using a transformer base editor to reactivate fetal haemoglobin production, led to early and enduring transfusion independence in patients with β-thalassaemia.

Mirror-enhanced 4Pi-SMLM with one objective enables isotropic nanoscale imaging

Nature Biotechnology - Issue - nature.com science feeds

By: Zijing Yu · Bei Zheng · Yajing Zhan · Shuxin Li · Xulong Wang · Qiuyang Dai · Yanqin Chen · Zongfang Wei · Wenxuan Zhao · Linlin Chen · Jiaxin Tang · Tianchang Xia · Lingjuan He · Changliang Liu · Xudong Wu · Xiaochun Yu · Yongdeng Zhang

31 March 2026 at 08:00

Nature Biotechnology, Published online: 31 March 2026; doi:10.1038/s41587-026-03083-7

Single-molecule 4Pi microscopy is simplified and made accessible by using a single objective.

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