Yibo et al. identify protein pyruvylation as a post-translational modification that can modulate immune signaling and host antiviral response.

Oncogene, Published online: 24 March 2026; doi:10.1038/s41388-026-03728-6

TRIM21-mediated degradation of HILPDA overcomes anti-PD-1 immunotherapy resistance in breast cancer by limiting PD-L1 palmitoylation

Oncogene, Published online: 23 March 2026; doi:10.1038/s41388-026-03734-8

PAK4 functions as an immune suppressor by reprogramming the phosphatidylcholine metabolism of CD8 + T cells within the glioblastoma tumor microenvironment

Nature Biotechnology, Published online: 13 March 2026; doi:10.1038/s41587-026-03057-9

A trispecific macrophage engager amplifies the antitumor response of macrophages in solid tumors.

Oncogene, Published online: 06 March 2026; doi:10.1038/s41388-026-03720-0

C-Jun-activated S100A10 promotes malignant progression via in diminishing ubiquitin-dependent degradation of vimentin in gastric cancer