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Genetically encoded fluorescent reporters to visualize Ξ±-synuclein pathology in live brain

βœ‡Cell
By: Li Zhang Β· Minhui Yu Β· Guoqing Chen Β· Siyuan Ge Β· Mengdi Wang Β· Xianying Zhang Β· Miao Zhao Β· Huating Gu Β· Meizhu Huang Β· Aixue Liu Β· Gengxin Ran Β· Zeyuan Liu Β· Tiepeng Liao Β· Qi Chen Β· Chenjian Miao Β· Yao Lu Β· Yibing Wang Β· Fengchao Wang Β· Zhihui Liu Β· Hongying Zhu Β· Qian Wu Β· Zhuan Zhou Β· Wei Xiong Β· Xiaoqun Wang Β· Peng Cao
The development of genetically encoded fluorescent reporters, along with their corresponding knock-in mouse lines for labeling Ξ±-Syn inclusions, enables diverse applications in studying the propagation and pathological effects of Ξ±-Syn inclusions in the live brain.
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