Oncogene, Published online: 11 April 2026; doi:10.1038/s41388-026-03772-2

Suppression of PP2A-B56α drives EMT in EGFR mutant non-small cell lung cancer

Nature, Published online: 10 April 2026; doi:10.1038/s41586-026-10484-w

Author Correction: Multi-omic profiling reveals age-related immune dynamics in healthy adults

Oncogene, Published online: 10 April 2026; doi:10.1038/s41388-026-03731-x

Wnt signaling and the tumor microenvironment: implications for cancer progression and therapeutics

Cell Death Discovery, Published online: 10 April 2026; doi:10.1038/s41420-026-03023-z

Berry-derived gold nanoparticles induce integrated ROS-mediated apoptosis, immune modulation, and transcriptomic remodeling in 4T1 triple-negative cancer cells

npj Digital Medicine, Published online: 10 April 2026; doi:10.1038/s41746-026-02583-9

Predicting bilingual aphasia treatment outcomes using digital twins: a double-blind randomized controlled trial

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10365-2

Assessment of how 16 taxonomic groups in a lowland tropical forest resist and recover from anthropogenic disturbance shows the potential of protecting naturally regenerating secondary forests to reverse biodiversity losses.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10334-9

Saturation genome editing of RNU4-2 identifies the functional and clinical impact of variants across the entire gene and delineates variants that cause a new recessive neurodevelopmental disorder distinct from ReNU syndrome.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10349-2

Across 17 forest plots (2.7 million trees, 5,400 species), competition dominated overall, but facilitation was relatively stronger near the equator and declined towards higher latitudes, partly linked to temperature, legumes, mycorrhizal associations and canopy nursing effect.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10337-6

An in vitro toolkit for studying VSG diversification defines key molecular requirements underlying the formation of mosaic VSGs, providing an experimental framework for the exploration of antigen diversification in Trypanosoma brucei and in other pathogenic microorganisms.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10316-x

A single-cell multiomic atlas of the human maternal–fetal interface across pregnancy reveals cell types, states and spatial niches, developmental tissue architectures and transcriptional programmes, and identifies cell types with roles in pre-eclampsia, spontaneous preterm birth and miscarriage.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10168-5

The CMS experiment at CERN reports one of the highest-precision measurements of the W boson mass, finding it in line with standard model predictions and at odds with recent anomalous measurements.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10330-z

Identification of genetic variants associated with the efficacy and side effects of GLP1 medications could underpin development of precision medicine approaches in the treatment of obesity.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10307-y

A mummified fossil of the early Permian reptile Captorhinus reveals the potential ancestral amniote breathing mechanism and its impact on terrestrial vertebrate evolution.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10326-9

The Human Development Multiomic Atlas catalogues single-cell accessibility and gene expression data from human fetal cells across 12 organs, enabling the inference of syntactic rules for motifs that govern cell-type-specific transcription factor binding and chromatin accessibility during human development.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10345-6

Decreased brain volumes and increased NfL levels can be observed earlier than disease diagnosis in short-tandem-repeat-associated neurological diseases.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10329-6

Synthetic super-enhancers enable specific delivery of anticancer payloads, achieving tumour elimination after a single dose in a mouse model of aggressive glioblastoma.

Nature, Published online: 08 April 2026; doi:10.1038/d41586-026-00905-1

Genetic variants in GLP1R and GIPR, which encode targets of GLP-1-based medications, offer insights into why responses to these drugs vary and who might face adverse effects.

Nature Medicine, Published online: 07 April 2026; doi:10.1038/s41591-026-04307-8

In a phase 1 basket trial, the small interfering RNA zodasiran, targeting ANGPTL3, lowered triglycerides in patients with severe hypertriglyceridemia and lowered both triglycerides and low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolemia.

Nature Medicine, Published online: 06 April 2026; doi:10.1038/s41591-026-04282-0

In the phase 3 EMN24 IsKia trial, transplant-eligible patients with newly diagnosed multiple myeloma who received isatuximab with carfilzomib, lenalidomide and dexamethasone pretransplant induction and post-transplant consolidation showed higher rates of measurable residual disease negativity after consolidation than patients who received carfilzomib, lenalidomide and dexamethasone.

Nature Medicine, Published online: 06 April 2026; doi:10.1038/s41591-026-04287-9

Analysis of neuroimaging datasets across five major psychedelics revealed a shared brain signature and provides a comprehensive insight into how these drugs reorganize brain architecture.