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De novo design of miniproteins targeting GPCRs
Nature, Published online: 21 May 2026; doi:10.1038/s41586-026-10656-8
De novo design of miniproteins targeting GPCRs
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circPARPBP promotes cancer stemness and chemoresistance in triple-negative breast cancer through recruiting SRCAP complex to activate CCL20 transcription
Oncogene, Published online: 21 May 2026; doi:10.1038/s41388-026-03819-4
circPARPBP promotes cancer stemness and chemoresistance in triple-negative breast cancer through recruiting SRCAP complex to activate CCL20 transcription
Clinical application of base editing for treating β-thalassaemia
Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10342-9
A clinical phase 1 trial of a single infusion of CS-101, CD34+ cells modified using a transformer base editor to reactivate fetal haemoglobin production, led to early and enduring transfusion independence in patients with β-thalassaemia.
Integrating large language models for enhanced predictive analytics in healthcare
npj Digital Medicine, Published online: 02 April 2026; doi:10.1038/s41746-026-02572-y
Integrating large language models for enhanced predictive analytics in healthcare
Structure of the mouse cytoplasmic lattice
Nature, Published online: 31 March 2026; doi:10.1038/s41586-026-10442-6
Structure of the mouse cytoplasmic lattice