Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10485-9
Bright squeezed vacuum light boosts nonlinear atomic tunnelling ionization more than 20-fold compared with coherent light, enabling quantum control of strong-field processes without increasing classical intensity.Reading view
Targeting cysteinyl leukotriene receptor 1 reprograms tumor-promoting myelopoiesis and overcomes immune checkpoint therapy resistance
Nature Cancer, Published online: 19 May 2026; doi:10.1038/s43018-026-01174-7
Tang et al. identify cysteinyl leukotriene receptor 1 (CysLTR1) as a critical regulator of tumor-induced myelopoiesis, suggesting CysLTR1 targeting to sensitize tumors to immune checkpoint blockade.Engineered immunosuppressive dendritic cells protect against cardiac remodelling
Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10346-5
Lesion-targeted immune modulation is a feasible strategy to control cardiac fibrosis, and engineered dendritic cells are a promising therapeutic platform for treating cardiac remodelling and heart failure.Superconductivity and electronic structures of nickelate thin film superstructures
Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10352-7
Engineered Ruddlesden–Popper nickelate superstructures show that specific Fermi surface features enable ambient-pressure superconductivity, linking structural configuration, electronic structure and superconducting behaviour. .Sequence Display enables large-scale sequence–activity datasets for rapid protein evolution
Nature Biotechnology, Published online: 08 April 2026; doi:10.1038/s41587-026-03087-3
Sequence Display maps protein variant activities to a sequencing-based readout.NSUN2/ALYREF-mediated RNA m5c modification promotes anoikis resistance of prostate cancer through activating autophagy
Oncogene, Published online: 07 April 2026; doi:10.1038/s41388-026-03762-4
NSUN2/ALYREF-mediated RNA m5c modification promotes anoikis resistance of prostate cancer through activating autophagyGenetically encoded fluorescent reporters to visualize α-synuclein pathology in live brain
The development of genetically encoded fluorescent reporters, along with their corresponding knock-in mouse lines for labeling α-Syn inclusions, enables diverse applications in studying the propagation and pathological effects of α-Syn inclusions in the live brain.
p63 in skin homeostasis and disease: molecular mechanisms and therapeutic potentials
Cell Death Discovery, Published online: 24 March 2026; doi:10.1038/s41420-026-03060-8
p63 in skin homeostasis and disease: molecular mechanisms and therapeutic potentials