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XPO1 inhibitor KPT-330 disrupts the core transcriptional regulatory circuitry of dedifferentiated liposarcoma by modulating the translation process

Oncogene, Published online: 16 April 2026; doi:10.1038/s41388-026-03794-w

XPO1 inhibitor KPT-330 disrupts the core transcriptional regulatory circuitry of dedifferentiated liposarcoma by modulating the translation process
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Genetically encoded fluorescent reporters to visualize Ξ±-synuclein pathology in live brain

The development of genetically encoded fluorescent reporters, along with their corresponding knock-in mouse lines for labeling Ξ±-Syn inclusions, enables diverse applications in studying the propagation and pathological effects of Ξ±-Syn inclusions in the live brain.
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