Nature, Published online: 16 March 2026; doi:10.1038/s41586-026-10179-2

A machine-learning model that integrates data from wearable devices (such as smartwatches) with blood biomarkers and demographic data can predict whether someone has insulin resistance, enabling timely lifestyle interventions to prevent progression to type 2 diabetes.

Nature, Published online: 16 March 2026; doi:10.1038/d41586-026-00422-1

Almost half of the scientists who responded said they have or had second jobs during their degrees.

Nature Medicine, Published online: 16 March 2026; doi:10.1038/s41591-026-04275-z

Artificial intelligence models are evolving from chats to hypotheses. Now their ideas are being validated in organoids and animals — and even in early-stage clinical trials.

Nature Medicine, Published online: 16 March 2026; doi:10.1038/s41591-026-04306-9

In cohort 4 of the ILUSTRO trial, combination of anti-CLDN18.2 zolbetuximab plus mFOLFOX6 and nivolumab in patients with CLDN18.2-positive, HER2-negative metastatic gastric or gastroesophageal junction adenocarcinoma led to encouraging clinical efficacy, supporting the testing of this combination in a phase 3 trial.

Cell Death Discovery, Published online: 15 March 2026; doi:10.1038/s41420-026-03015-z

Misregulated alternative splicing in endometriosis: a role for aberrant mRNA variants in endometriotic cell growth