Nature Biomedical Engineering, Published online: 06 October 2026; doi:10.1038/s41551-026-01786-5

A nanoscale metal–organic framework (MOF)-based cancer vaccine platform enables coordinated antigen presentation and innate immune activation, resulting in tumour regression, immune memory and protection against metastasis.

Nature Biomedical Engineering, Published online: 06 October 2026; doi:10.1038/s41551-026-01780-x

A long-term flexible electrode array system stably tracks individual neurons for months, revealing intrinsic drift in visual evoked neural activity and potentiating durable cross-session and cross-animal decoding.

Nature Biomedical Engineering, Published online: 05 October 2026; doi:10.1038/s41551-026-01805-5

This Review highlights how organoids and organ-on-a-chip technologies are transforming gastrointestinal disease research by providing clinically relevant models of inflammation, infection and cancer and discusses future opportunities for therapeutic developments.

Nature Biomedical Engineering, Published online: 05 October 2026; doi:10.1038/s41551-026-01806-4

Multi-organ-on-a-chip systems aim to improve the prediction of human drug responses by replicating organ interactions in vitro. This Review discusses advances in niche-preserving engineering, scalable manufacturing and multimodal readouts needed to make these systems reliable tools.

Nature Biomedical Engineering, Published online: 05 October 2026; doi:10.1038/s41551-026-01798-1

A positron emission tomography tracer that directly targets bacterial metabolism by exploiting the phosphotransferase system, a carbohydrate transport pathway absent in mammalian cells, enables selective detection of living bacteria in vivo.

Nature Nanotechnology, Published online: 05 October 2026; doi:10.1038/s41565-026-02301-2

Multiscale physicochemical and electrochemical characterizations demonstrate that atomic-scale structural distortion and nanoscale short-range ordering govern the thermodynamic and kinetic components of potential hysteresis in Li||DRX cells.

Nature Nanotechnology, Published online: 29 September 2026; doi:10.1038/s41565-026-02298-8

A torsion-pendulum gravitational-force sensor with an optical microcavity readout leverages coupled photon–phonon effects to enhance sensitivity to the tiny gravitational pull from a millimetre-sized source mass.

Nature Nanotechnology, Published online: 29 September 2026; doi:10.1038/s41565-026-02280-4

Four-inch rhombohedral-stacked boron nitride wafers are reproducibly synthesized through a step-templated interfacial epitaxy strategy, exhibiting high-density, fast-speed and non-volatile memory performances.

Nature Biomedical Engineering, Published online: 28 September 2026; doi:10.1038/s41551-026-01815-3

Author Correction: Intermittent hypobaric pressure induces selective senescent cell death and alleviates age-related osteoporosis

Nature Nanotechnology, Published online: 28 September 2026; doi:10.1038/s41565-026-02284-0

MRI-responsive hydrogel microparticles embedded with zinc ferrite nanoparticles enable deep-tissue mapping of dynamic tumour compression, revealing that transient stress surges, rather than cumulative mechanical load, lead to the epithelial–mesenchymal transition and tumour remodelling.

Nature Nanotechnology, Published online: 28 September 2026; doi:10.1038/s41565-026-02282-2

Magnetic-resonance-responsive sensors comprising zinc ferrite nanoparticles embedded in hydrogel microparticles enable mapping of tissue stress, revealing that acute stress surges, rather than cumulative mechanical load, drive epithelial–mesenchymal transition and tumour remodelling.

Nature Biomedical Engineering, Published online: 23 September 2026; doi:10.1038/s41551-026-01791-8

Unsaturated phospholipids unexpectedly form multilamellar, multivesicular liposomes that efficiently encapsulate hydrophilic drugs and suppress burst release. These structures enable ultra-slow drug release and produce weeks-long sciatic nerve block with tetrodotoxin in rats.

Nature Biomedical Engineering, Published online: 23 September 2026; doi:10.1038/s41551-026-01793-6

Contrary to expectations that unsaturation accelerates release, unsaturated phospholipid liposomes showed 3-fold higher loading and markedly reduced initial and sustained release due to multilamellar–multivesicular structure.

Nature Nanotechnology, Published online: 17 September 2026; doi:10.1038/s41565-026-02274-2

Two-dimensional materials offer low resistivity, strong thermal management and back-end-of-line compatibility, making them promising for advanced interconnects, backside power delivery and boosting efficiency in next-generation semiconductor chips.

Nature Nanotechnology, Published online: 15 September 2026; doi:10.1038/s41565-026-02276-0

Monolithic 3D integration of oxide semiconductor devices on a 200-mm wafer is demonstrated, enabling vertically interconnected logic and memory and supporting the design of an energy-efficient AI accelerator.

Nature Nanotechnology, Published online: 14 September 2026; doi:10.1038/s41565-026-02278-y

Thermally assisted intaglio transfer printing and interfacial ligand engineering turn quantum dots into stretchable, ultrabright and high-definition displays.

Nature Nanotechnology, Published online: 14 September 2026; doi:10.1038/s41565-026-02272-4

Innovative ligand engineering and thermally assisted intaglio transfer printing enhance charge injection and pixel resolution in stretchable quantum-dot light-emitting diodes, achieving high efficiencies and luminance while maintaining mechanical integrity under deformation.

Nature Nanotechnology, Published online: 14 September 2026; doi:10.1038/s41565-026-02254-6

This work demonstrates a parallelized four-qubit entangling gate on a room-temperature spin register, and it operates ten times faster than sequences of two-qubit gates with reduced errors.

Nature Nanotechnology, Published online: 14 September 2026; doi:10.1038/s41565-026-02281-3

This study demonstrates on-chip all-optical switching by integrating magnetic memory elements with photonic circuits, establishing a route towards fully integrated magneto-photonic systems for ultrafast and energy-efficient information technologies.

Abstract

Microsized silicon monoxide (SiO) anodes have attracted considerable attention owing to their high theoretical specific capacity, but their low electronic conductivity and severe volume expansion during cycling hinder practical application. Herein, a synergistic dual-coating strategy is developed to construct a trilayer SiO@SiO_x/C@ZC composite anode composed of a SiO core, a homogeneous SiO_x/C composite interlayer, and a ZIF-8-derived carbon outer shell containing uniformly anchored Zn-containing inorganic nanoparticles. γ-Mercaptopropyltrimethoxysilane (MPTMS) was first coated onto SiO, where thiol groups anchored ZIF-8 precursors through coordination with Zn²⁺. After high-temperature calcination, the MPTMS-derived homogeneous SiO_x/C interlayer buffered volume expansion and improved structural stability, while the ZIF-8-derived carbon shell enhanced electronic conductivity and constructed a continuous carbon network. The Zn-containing inorganic nanoparticles embedded within the carbon shell further facilitated interfacial Li⁺ transport. SiO@SiO_x/C@ZC retained 885.72 mAh g⁻¹ after 1000 cycles at 1 A g⁻¹ with 84.2% capacity retention and delivered 553 mAh g⁻¹ at 10 A g⁻¹. Chemical prelithiation was further employed to compensate for the initial irreversible lithium loss and improve lithium utilization, enabling the SiO@SiO_x/C@ZC//NCM811 full cell to maintain 150 mAh g⁻¹ after 200 cycles at 1 C and to retain 70.86% of its capacity at 6 C during rate testing. This work provides an efficient strategy for practical microsized SiO anodes.