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Landscape analysis of m5C modification regulators unveils DNMT1-mediated dysregulated pyrimidine metabolism in hepatocellular carcinoma

Most Recent Articles: Clinical Epigenetics

By: Xuhui Zhao, Shengwei Mao, Yuan Fang, Jiafeng Chen, Lifu Bi, Jie Li, Jinglei Wu, Jun Gao, Shiguang Yang, Jialu Fu, Xiaoling Wu, Guiqi Zhu, Zheng Tang, Yinghong Shi, Jian Zhou, Jia Fan&hellip

22 August 2025 at 08:00

The 5-methylcytosine (m5C) post-transcriptional modification has been linked with the development and progression of a variety of cancers. However, its specific functions and their underlying mechanisms are po...

RASGEF1C methylation for the distinguishment and classification of benign and malignant thyroid tumors

Most Recent Articles: Clinical Epigenetics

By: Wenkang Yu · Yifei Yin · Mengxia Li · Haixia Huang · Junjie Li · Yi Zhang · Lun Zhu · Yifen Zhang · Xuandong Huang · Chenxia Jiang and Rongxi Yang

14 July 2025 at 08:00

The incidence of thyroid cancer (TC) has significantly increased, highlighting the need for effective and objective approaches for the early diagnosis of TC. This study aimed to explore RASGEF1C methylation as a ...