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Does polypharmacy affect epigenetic aging in older people? Evidence from a longitudinal epigenome-wide methylation study

βœ‡Most Recent Articles: Clinical Epigenetics
By: Alessandro Gialluisi Β· Alfonsina Tirozzi Β· Simona Costanzo Β· Danilo Licastro Β· Augusto Di Castelnuovo Β· Miriam Shasa Quiccione Β· Stefania Falciglia Β· Margherita Degasperi Β· Teresa Panzera Β· Sara Magnacca Β· Mariarosaria Persichillo Β· Fabrizia Noro Β· Chiara Cerletti Β· Maria Benedetta Donati Β· Giovanni de Gaetano and Licia Iacoviello
Polypharmacy, defined as taking β‰₯ 5 different daily medications, is common in older adults and has been linked with neuropsychiatric/neurological and other health conditions. To clarify the potential molecular...
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Unraveling the causal association of epigenetic age acceleration with common oral diseases and its underlying mechanisms: findings from Mendelian randomization and integrative genetic analysis

βœ‡Most Recent Articles: Clinical Epigenetics
By: Lianjie Peng Β· Shengzhe Nie Β· Yihua Sun Β· Shihan Wang Β· Yaying Wang and Zhichao Liu
The epigenetic clock is recognized as a highly accurate predictor of biological aging, but the relationship between epigenetic age acceleration and oral diseases remains poorly understood. This study aimed to ...
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