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Hijacking ERAD for targeted degradation of transmembrane proteins

βœ‡Cell
By: Haikun Song Β· Wei Wang Β· Tingfang Mei Β· Huiwen Zheng Β· Keni Ning Β· Xiaofan Liu Β· Siulam Cheung Β· Zhiyuan Cao Β· Danqi Sheng Β· Xiaohan Mai Β· Haoran Zhu Β· Guankai Guo Β· Shuaimeng Liu Β· Rongkai Wei Β· Qian Wang Β· Yu Cao Β· Yu Ding Β· Yiyan Fei Β· Rui Liu Β· Motoyuki Hattori Β· Chunquan Sheng Β· Boxun Lu
Development of an ERAD-hijacking technology overcomes the challenges of current targeted protein degradation approaches to achieve degradation of transmembrane proteins.
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