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An activated wheat CCG10-NLR immune receptor forms an octameric resistosome

Cell

By: Guanghao Guo · He Zhao · Kaihong Bai · Jian Lu · Qiuhong Wu · Lei Lu · Yue Zhang · Lingli Dong · Guangwei Li · Yongxing Chen · Yikun Hou · Ping Lu · Miaomiao Li · Huaizhi Zhang · Gaojie Wang · Keyu Zhu · Baoge Huang · Xuejia Cui · Hongkui Fu · Chenchen Hu · Zhiying Chu · Xue Lyu · Sophien Kamoun · Chao Wang · Zhiyong Liu · Muniyandi Selvaraj · Jonathan D.G. Jones

20 March 2026 at 08:00

An activated CCG10-NLR WAI3 plant immune receptor forms an octameric resistosome, which induces calcium influx and immune responses through a unique channel architecture.

Transplantation of encapsulated mitochondria alleviates dysfunction in mitochondrial and Parkinson’s disease models

Cell

By: Shiwei Du · Qi Long · Yanshuang Zhou · Jiangqin Fu · Hao Wu · Liang Yang · Yaohang Xie · Yingzhe Ding · Maolei Zhang · Jingyi Guo · Mengfei Wang · Jiajun Lin · Mingli Hu · Jian Zhang · Deyang Yao · Wei Li · Feixiang Bao · Ge Xiang · Yi Wu · Yile Huang · Haozhao Liang · Rui Wang · Heying Li · Baodan Chen · Chong Li · Junwei Wang · Jiwei Zhang · Dajiang Qin · Jianwei Sun · Yun Zhu · Fei Sun · Wuming Wang · Gang Lu · Wai-Yee Chan · Hui Zhao · Chenli Liu · Xingguo Liu

18 March 2026 at 08:00

A mitochondrial transplantation approach rescues mitochondrial deficiency and prevents mitochondrial DNA depletion syndrome, Leigh syndrome, and Parkinson’s disease in cellular and mouse models.