Cell Death Discovery, Published online: 11 September 2026; doi:10.1038/s41420-026-03338-x

Fibronectin 1 mediated histone lactylation promotes malignant progression of GIST regulated by m⁶A modification

Cell Death Discovery, Published online: 10 September 2026; doi:10.1038/s41420-026-03334-1

Metformin-mediated immunometabolic rewiring attenuates type I interferon-driven dendritic cell inflammation in STAT1 gain-of-function

Cell Death Discovery, Published online: 09 September 2026; doi:10.1038/s41420-026-03332-3

Multi-omic profiling reveals metabolic vulnerabilities in enzalutamide resistant prostate cancer

Cell Death Discovery, Published online: 09 September 2026; doi:10.1038/s41420-026-03340-3

Checkpoint kinase 2 deficiency affects the engagement of DNA double-strand break repair pathways following DNA damage

Cell Death Discovery, Published online: 09 September 2026; doi:10.1038/s41420-026-03337-y

Reorientation of the SUMOylation landscape and altered L3mbtl2-mediated transcriptional activity in cancer-associated muscle contractile dysfunction

Cell Death Discovery, Published online: 08 September 2026; doi:10.1038/s41420-026-03339-w

Lipotoxicity-induced ER-mitochondrial hypercoupling activates the mtDNA-cGAS-STING-NF-κB axis to drive follicular arrest in metabolically compromised PCOS

Cell Death Discovery, Published online: 07 September 2026; doi:10.1038/s41420-026-03299-1

G9a-mediated cholesterol metabolism triggers cuproptosis to promote alcohol-related liver disease

Cell Death Discovery, Published online: 03 September 2026; doi:10.1038/s41420-026-03327-0

Arrest of human spermatogenesis at the pachytene stage is frequently accompanied by disruption of the piRNA pathway

Cell Death Discovery, Published online: 01 September 2026; doi:10.1038/s41420-026-03316-3

Concurrent upregulation of autophagic flux and induction of the SQSTM1/p62-VCAM-1 axis deter radiosensitivity of triple-negative breast cancer cells

Cell Death Discovery, Published online: 01 September 2026; doi:10.1038/s41420-026-03324-3

MUC13 promotes cisplatin resistance in intrahepatic cholangiocarcinoma through regulation by histone H3K18 lactylation

Cell Death Discovery, Published online: 01 September 2026; doi:10.1038/s41420-026-03315-4

The insulin-like growth factor 2 mRNA-binding protein 2 affects tumor cell metabolism via mitochondrial transporter activity and lipid alterations

Cell Death Discovery, Published online: 31 August 2026; doi:10.1038/s41420-026-03306-5

Ibrutinib-triggered matriptase maintains extracellular CD19 and limits antigen escape in B-cell malignancy

Cell Death Discovery, Published online: 31 August 2026; doi:10.1038/s41420-026-03309-2

PLCE1 exacerbates the development of atherosclerosis by driving endothelial dysfunction and macrophage inflammation via targeting CTNNB1

Cell Death Discovery, Published online: 26 May 2026; doi:10.1038/s41420-026-03151-6

Reprogramming temozolomide response in glioblastoma through regulated and immunogenic cell death modalities

Cell Death Discovery, Published online: 26 May 2026; doi:10.1038/s41420-026-03165-0

Activation of methionine metabolism mediated by HNF4α confers ferroptosis resistance in hepatocellular carcinoma

Cell Death Discovery, Published online: 25 May 2026; doi:10.1038/s41420-026-03128-5

Deubiquitinase USP35 regulates MDM4 degradation to promote endothelial ferroptosis and renal injury progression

Cell Death Discovery, Published online: 25 May 2026; doi:10.1038/s41420-026-03142-7

ATP2B4 driven chromatin compaction exacerbates pancreatic cancer radiotherapy resistance

Cell Death Discovery, Published online: 25 May 2026; doi:10.1038/s41420-026-03166-z

Hippocampal small RNAs from patients with schizophrenia induce specific cognitive and neural phenotypes in mice

Cell Death Discovery, Published online: 23 May 2026; doi:10.1038/s41420-026-03147-2

Ferroptosis and macrophage polarization: mechanisms, interplay, and implications for medical applications

Cell Death Discovery, Published online: 23 May 2026; doi:10.1038/s41420-026-03167-y

S100A4–TLR4–TGF-β axis as a therapeutic target for Dupuytren’s contracture in diabetic patients