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Genomic history of early dogs in Europe

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10112-7

Genome-wide analysis shows European dogs existed by 14,200 years ago, were already genetically distinct, received less Neolithic Southwest Asian admixture than humans did and contributed substantially to later European dogs.
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Exposed phosphatidylserine is an inhibitory molecule in T cell exhaustion

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10266-4

Insights into the mechanism by which phosphatidylserine functions as a non-classical inhibitory molecule during T cell exhaustion, and how phosphatidylserine-targeting antibodies enhance T cell responses are explored.
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A fast starburst wind consumes most of the energy from supernovae

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10231-1

Starburst galaxies are seen to host galaxy-scale winds, which are super-fast and could be powered entirely by the thermal pressure of gas heated by supernovae.
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Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10264-6

Androgen activity in the male embryonic hindbrain prolongs hindbrain differentiation in male individuals and drives sex differences in the incidence and prognosis of posterior fossa type A (PFA) ependymoma, an aggressive childhood brain tumour.
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Rapid concerted switching of the neural code in the inferotemporal cortex

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10267-3

Face cells in the macaque inferotemporal cortex are initially able to detect faces and then rapidly switch to a face-specific neural code to discriminate between different face identities.
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Decadal-scale droughts disrupted the African Humid Period in the Sahara

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10336-7

Sedimentary time-series data of Lake Yoa in Chad covering the past 10.25 thousand years (kyr) show that the mid-Holocene African Humid Period experienced several decadal-scale droughts, caused by sudden inputs of freshwater into the North Atlantic.
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A large-scale coherent 4D imaging sensor

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10183-6

A 4D imaging architecture using a large-scale, coherent LiDAR focal plane array comprising more than 0.6 million photonic components and associated electronics integrated on-chip can obtain coherent images at high frame rates over useful distances.
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Multimodal electron microscopy of halide perovskite interfacial dynamics

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10238-8

A multimodal in situ electron microscopy approach enables direct visualization of structural and chemical evolution in a working halide perovskite light-emitting diode with nanometre precision.
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A sorghum pangenome reference improves global crop trait discovery

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10229-9

A pangenome reference for the phenotypically diverse crop sorghum aims to help accelerate future efforts to breed crops that are better adapted to changing environments.
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Gene conversion empowers natural selection in a clonal fish species

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10180-9

Analysis of the asexually reproducing Amazon molly Poecilia formosa and its sexually reproducing progenitors Poecilia mexicana and Poecilia latipinna reveals that it maintains a divergent mutational landscape and has evaded functional mutational decay via gene conversion.
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A mechanism to initiate emergency type 2 myelopoiesis

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10256-6

Myelopoiesis in response to a parasitic worm infection and the mechanism selective to this form of parasite are revealed.
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