arXiv:2602.19822v1 Announce Type: cross Abstract: Early detection of myometrial invasion is critical for the staging and life-saving management of endometrial carcinoma (EC), a prevalent global malignancy. Transvaginal ultrasound serves as the primary, accessible screening modality in resource-constrained primary care settings; however, its diagnostic reliability is severely hindered by low tissue contrast, high operator dependence, and a pronounced scarcity of positive pathological samples. Existing artificial intelligence solutions struggle to overcome this severe class imbalance and the subtle imaging features of invasion, particularly under the strict computational limits of primary care clinics. Here we present an automated, highly efficient two-stage deep learning framework that resolves both data and computational bottlenecks in EC screening. To mitigate pathological data scarcity, we develop a structure-guided cross-modal generation network that synthesizes diverse, high-fidelity ultrasound images from unpaired magnetic resonance imaging (MRI) data, strictly preserving clinically essential anatomical junctions. Furthermore, we introduce a lightweight screening network utilizing gradient distillation, which transfers discriminative knowledge from a high-capacity teacher model to dynamically guide sparse attention towards task-critical regions. Evaluated on a large, multicenter cohort of 7,951 participants, our model achieves a sensitivity of 99.5\%, a specificity of 97.2\%, and an area under the curve of 0.987 at a minimal computational cost (0.289 GFLOPs), substantially outperforming the average diagnostic accuracy of expert sonographers. Our approach demonstrates that combining cross-modal synthetic augmentation with knowledge-driven efficient modeling can democratize expert-level, real-time cancer screening for resource-constrained primary care settings.

arXiv:2510.11608v2 Announce Type: replace Abstract: Large Language Models (LLMs) exhibit strong reasoning abilities for planning long-horizon, real-world tasks, yet existing agent benchmarks focus on task completion while neglecting time efficiency in parallel and asynchronous operations. To address this, we present ParaCook, a benchmark for time-efficient collaborative planning. Inspired by the Overcooked game, ParaCook provides an environment for various challenging interaction planning of multi-agent systems that are instantiated as cooking tasks, with a simplified action space to isolate the core challenge of strategic parallel planning. Through a comprehensive evaluation of state-of-the-art LLMs, we find that current approaches achieve suboptimal plans, which struggle with parallel actions or coordination. Our analysis also reveals LLMs' potential on abstract tasks where they can focus on high-level parallel optimization. ParaCook provides a scalable evaluation framework with adjustable complexity, establishing a foundation for developing and assessing time efficiency-aware multi-agent planning. The code and data are available at https://github.com/zsq259/ParaCook.