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An epigenetic barrier sets the timing of human neuronal maturation

βœ‡Nature - Issue - nature.com science feeds
By: Gabriele Ciceri Β· Arianna Baggiolini Β· Hyein S. Cho Β· Meghana Kshirsagar Β· Silvia Benito-Kwiecinski Β· Ryan M. Walsh Β· Kelly A. Aromolaran Β· Alberto J. Gonzalez-Hernandez Β· Hermany Munguba Β· So Yeon Koo Β· Nan Xu Β· Kaylin J. Sevilla Β· Peter A. Goldstein Β· Joshua Levitz Β· Christina S. Leslie Β· Richard P. Koche Β· Lorenz Studer

Nature, Published online: 31 January 2024; doi:10.1038/s41586-023-06984-8

The slow maturation of human neurons is regulated by epigenetic modification in nascent neurons, mediated by EZH2, EHMT1, EHMT2 and DOT1L.
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