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Fluctuating DNA methylation tracks cancer evolution at clinical scale

βœ‡Nature - Issue - nature.com science feeds
By: Calum Gabbutt Β· MartΓ­ Duran-Ferrer Β· Heather E. Grant Β· Diego Mallo Β· Ferran Nadeu Β· Jacob Househam Β· Neus Villamor Β· Madlen MΓΌller Β· Simon Heath Β· Emanuele Raineri Β· Olga Krali Β· Jessica Nordlund Β· Thorsten Zenz Β· Ivo G. Gut Β· Elias Campo Β· Armando Lopez-Guillermo Β· Jude Fitzgibbon Β· Chris P. Barnes Β· Darryl Shibata Β· JosΓ© I. Martin-Subero Β· Trevor A. Graham

Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09374-4

Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.
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