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Do their ears hang low? The genetics of dogsβ adorable floppy ears
Nature, Published online: 13 January 2026; doi:10.1038/d41586-026-00071-4
Scientists are just beginning to understand the signals that determine the length of dogsβ ears.
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How to fix genetic βnonsenseβ: versatile gene-editing tool could tackle a host of diseases
Nature, Published online: 19 November 2025; doi:10.1038/d41586-025-03770-6
Synthetic RNA molecules can program cells to ignore DNA mutations that interfere with protein production.
Personalized gene editing helped one baby: can it be rolled out widely?
Nature, Published online: 31 October 2025; doi:10.1038/d41586-025-03566-8
In a world first, a bespoke gene-editing therapy benefited one child. Now researchers plan to launch a clinical trial of the approach.
Ageing accelerates at around age 50 β some organs faster than others
Nature, Published online: 25 July 2025; doi:10.1038/d41586-025-02333-z
An analysis of how various tissues age is the latest to suggest that ageing does not march to a steady beat.
Worldβs first personalized CRISPR therapy given to baby with genetic disease
Nature, Published online: 15 May 2025; doi:10.1038/d41586-025-01496-z
Treatment seems to have been effective, but it is not clear whether such bespoke therapies can be widely applied.
How quickly are you ageing? What molecular βclocksβ can tell you about your health
Nature, Published online: 25 February 2025; doi:10.1038/d41586-025-00566-6
Armed with an influx of cash and public enthusiasm, researchers are looking to improve how ageing is measured.
Why eating less slows ageing: this molecule is key
Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04220-5
A naturally occurring compound involved in digestion lengthens lifespan in flies and makes old mice more youthful.
Why cancer risk declines sharply in old age
Nature, Published online: 02 July 2024; doi:10.1038/d41586-024-02107-z
New research identifies some of the genes that could help to explain why lung cancer incidence rises with age but declines after the age of 75.
Audio long read: Why are so many young people getting cancer? What the data say
Nature, Published online: 05 April 2024; doi:10.1038/d41586-024-00884-1
Researchers are scrambling to explain why rates of multiple cancers are increasing among adults under the age of 50.
CRISPR 2.0: a new wave of gene editors heads for clinical trials
Nature, Published online: 07 December 2023; doi:10.1038/d41586-023-03797-7
Landmark approval of the first CRISPR therapy paves the way for treatments based on more efficient and more precise genome editors.
How the Y chromosome makes some cancers more deadly for men
Nature, Published online: 21 June 2023; doi:10.1038/d41586-023-01987-x
Two studies help to explain why colorectal and bladder tumours take a bigger toll on men than on women.
US cancer deaths are falling β but not fast enough
Nature, Published online: 27 April 2023; doi:10.1038/d41586-023-01444-9
Models show that death rates must decline faster to meet Cancer Moonshot goals to cut deaths in half in 25 years.
Why CRISPR babies are still too risky β embryo studies highlight challenges
Nature, Published online: 10 March 2023; doi:10.1038/d41586-023-00756-0
While society grapples with the social and ethical implications of heritable genome editing, technical obstacles still abound.
The mice with two dads: scientists create eggs from male cells
Nature, Published online: 09 March 2023; doi:10.1038/d41586-023-00717-7
Proof-of-concept mouse experiment will have a long road before use in humans is possible.
Cancer treatments boosted by immune-cell hacking
Nature, Published online: 15 December 2022; doi:10.1038/d41586-022-04465-y
Precision-controlled CAR-T-cell immunotherapies could be used to tackle a range of tumour types.
Trove of tumour genomes offers clues to cancer origins
Nature, Published online: 21 April 2022; doi:10.1038/d41586-022-01095-2
Largest-ever study uncovers patterns of mutations that might pinpoint cancerβs causes.