Cancer drug approvals and setbacks in 2025
Nature Cancer, Published online: 10 December 2025; doi:10.1038/s43018-025-01080-4
Bispecific antibodies and ADCs battle for the limelight, CAR-T therapy sees late surge and Chinaβs growth continues.Nature Cancer, Published online: 10 December 2025; doi:10.1038/s43018-025-01080-4
Bispecific antibodies and ADCs battle for the limelight, CAR-T therapy sees late surge and Chinaβs growth continues.Nature Biotechnology, Published online: 19 November 2025; doi:10.1038/s41587-025-02933-0
Biopharmaβs reawakened interest in cardiovascular diseases spans new targets and modalities, with more convenient formulations to boost access and adherence.Nature Cancer, Published online: 01 October 2025; doi:10.1038/s43018-025-01044-8
Investment continues as the field awaits phase 3 readouts for next-generation radioligand therapies in 2026.Nature Biotechnology, Published online: 13 December 2024; doi:10.1038/s41587-024-02506-7
Merger and acquisition activity is at a seven-year low in 2024 as buyers digest prior deals and US election jitters delayed further spending. Expect a pick-up in 2025.Nature Biotechnology, Published online: 12 June 2024; doi:10.1038/s41587-024-02295-z
Targeted radiopharmaceuticals offer resistance-free potency, pre-treatment imaging and widespread combination potential. Big pharma and investors are piling in.