Whole-genome sequencing of 490,640 UK Biobank participants

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By: Keren Carss · Bjarni V. Halldorsson · Liping Hou · Jimmy Liu · Eleanor Wheeler · Yancy Lo · Kousik Kundu · Zhuoyi Huang · Ben Lacey · Ryan S. Dhindsa · Diana Rajan · Jelena Randjelovic · Neil Marriott · Carol E. Scott · Ahmet Sinan Yavuz · Ian Johnston · Trevor Howe · Mary Helen Black · Kari Stefansson · Robert Scott · Slavé Petrovski · Shuwei Li · Adrian Cortes · Fengyuan Hu · Quanli Wang · Oliver S. Burren · Sri V. V. Deevi · Carolina Haefliger · Kieren Lythgow · Peter H. Maccallum · Karyn Mégy · Jonathan Mitchell · Sean O’Dell · Amanda O’Neill · Katherine R. Smith · Haeyam Taiy · Menelas Pangalos · Ruth March · Sebastian Wasilewski · Hannes P. Eggertsson · Kristjan H. S. Moore · Hannes Hauswedell · Ogmundur Eiriksson · Aron Skaftason · Nokkvi Gislason · Svanhvit Sigurjonsdottir · Magnus O. Ulfarsson · Gunnar Palsson · Marteinn T. Hardarson · Asmundur Oddsson · Brynjar O. Jensson · Snaedis Kristmundsdottir · Brynja D. Sigurpalsdottir · Olafur A. Stefansson · Doruk Beyter · Guillaume Holley · Vinicius Tragante · Arnaldur Gylfason · Pall I. Olason · Florian Zi

6 August 2025 at 08:00

Nature, Published online: 06 August 2025; doi:10.1038/s41586-025-09272-9

A study reports whole-genome sequences for 490,640 participants from the UK Biobank and combines these data with phenotypic data to provide new insights into the relationship between human variation and sequence variation.

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