GigaTIME leverages multimodal AI to generate virtual multiplex immunofluorescence (mIF) profiles from standard H&E slides, enabling comprehensive tumor immune microenvironment modeling across a large (>14,000) and diverse patient population. This virtual approach unlocks new opportunities for large-scale clinical discoveries that were previously hindered by the scarcity of mIF data.

Nature, Published online: 22 May 2024; doi:10.1038/s41586-024-07441-w

Prov-GigaPath, a whole-slide pathology foundation model pretrained on a large dataset containing around 1.3 billion pathology images, attains state-of-the-art performance in cancer classification and pathomics tasks.

Nature Biotechnology, Published online: 30 November 2022; doi:10.1038/s41587-022-01616-4

Author Correction: m⁶A RNA modifications are measured at single-base resolution across the mammalian transcriptome

Oncogenesis, Published online: 04 August 2022; doi:10.1038/s41389-022-00418-2

ZNF655 accelerates progression of pancreatic cancer by promoting the binding of E2F1 and CDK1