Epigenetic regulation during cancer transitions across 11 tumour types

Nature - Issue - nature.com science feeds

By: Nadezhda V. Terekhanova · Alla Karpova · Wen-Wei Liang · Alexander Strzalkowski · Siqi Chen · Yize Li · Austin N. Southard-Smith · Michael D. Iglesia · Michael C. Wendl · Reyka G. Jayasinghe · Jingxian Liu · Yizhe Song · Song Cao · Andrew Houston · Xiuting Liu · Matthe

1 November 2023 at 08:00

Nature, Published online: 01 November 2023; doi:10.1038/s41586-023-06682-5

A pan-cancer epigenetic and transcriptomic atlas identifies epigenetic drivers associated with cancer transitions.

Pan-cancer proteogenomics connects oncogenic drivers to functional states

Cell

By: Yize Li， Eduard Porta-Pardo， Collin Tokheim， Matthew H. Bailey， Tomer M. Yaron， Vasileios Stathias， Yifat Geffen， Kathleen J. Imbach， Song Cao， Shankara Anand， Yo Akiyama， Wenke Liu， Matthew A. Wyczalkowski， Yizhe Song， Erik P

14 August 2023 at 08:00

A multi-omics analysis-based resource across ten cancer types from more than 1,000 patients provides pan-cancer insights into shared oncogenic driver mechanisms and pathways.

Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation

Cell

By: Yifat Geffen， Shankara Anand， Yo Akiyama， Tomer M. Yaron， Yizhe Song， Jared L. Johnson， Akshay Govindan， Özgün Babur， Yize Li， Emily Huntsman， Liang-Bo Wang， Chet Birger， David I. Heiman， Qing Zhang， Mendy Miller， Yosef E.

14 August 2023 at 08:00

An analytical resource of post-translational modifications from over 1,000 patients across 11 cancer types reveals pan-cancer changes involved in hallmark cancer processes and reveals potential new therapeutic avenues.

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