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Predicting disease-free survival in colorectal cancer by circulating tumor DNA methylation markers

Most Recent Articles: Clinical Epigenetics

By: Xin Yang， Xiaofeng Wen， Qin Guo， Yunfeng Zhang， Zhenxing Liang， Qian Wu， Zhihao Li， Weimei Ruan， Zhujia Ye， Hong Wang， Zhiwei Chen， Jian-Bing Fan， Ping Lan， Huashan Liu and Xianrui Wu

1 December 2022 at 08:00

Recurrence represents a well-known poor prognostic factor for colorectal cancer (CRC) patients. This study aimed to establish an effective prognostic prediction model based on noninvasive circulating tumor DNA...

Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer

Nature - Issue - nature.com science feeds

By: Jorge Luis Galeano Niño · Hanrui Wu · Kaitlyn D. LaCourse · Andrew G. Kempchinsky · Alexander Baryiames · Brittany Barber · Neal Futran · Jeffrey Houlton · Cassie Sather · Ewa Sicinska · Alison Taylor · Samuel S. Minot · Christopher D. Johnston · Susan Bullman

16 November 2022 at 08:00

Nature, Published online: 16 November 2022; doi:10.1038/s41586-022-05435-0

Spatial profiling and single-cell RNA sequencing are used to map the spatial distribution of the microbiota within human tumours, revealing how intratumoral microbial communities contribute to tumour heterogeneity and cancer progression.