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A draft human pangenome reference

Nature, Published online: 10 May 2023; doi:10.1038/s41586-023-05896-x

An initial draft of the human pangenome is presented and made publicly available by the Human Pangenome Reference Consortium; the draft contains 94 de novo haplotype assemblies from 47 ancestrally diverse individuals.
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Pangenome graph construction from genome alignments with Minigraph-Cactus

Nature Biotechnology, Published online: 10 May 2023; doi:10.1038/s41587-023-01793-w

Constructing genome graphs directly from genome assemblies overcomes single-reference bias.
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