Rescuing dendritic cell interstitial motility sustains antitumour immunity

Nature - Issue - nature.com science feeds

By: Haichao Tang · Zongfang Wei · Bei Zheng · Yumeng Cai · Peihan Wu · Lulu Wu · Xiaohe Ma · Yanqin Chen · Si Su · Jinmin Xu · Yu Qiao · Ying Zhang · Juju Miao · Zijing Yu · Yaodong Zhao · Zhen Xia · Rongjing Zhou · Jian Liu · Jufeng Guo · Zhaoyuan Liu · Qi Xie · Florent Ginhoux · Luming Zhao · Xu Li · Bing Xia · Huanwen Wu · Yongdeng Zhang · Ting Zhou

25 June 2025 at 08:00

Nature, Published online: 25 June 2025; doi:10.1038/s41586-025-09202-9

Disruption of dendritic cell (DC) interstitial motility in the tumour microenvironment promotes immune evasion, and enhancement of DC interstitial motility offers a route for DC-centric immunotherapy.

Novel histone post-translational modifications in Alzheimer’s disease: current advances and implications

Most Recent Articles: Clinical Epigenetics

By: Yuanyuan Qin， Ping Yang， Wanhong He， Dongze Li， Lisha Zeng， Junle Li， Tingting Zhou， Juan Peng， Ling Cao and Wei Huang

9 March 2024 at 08:00

Alzheimer’s disease (AD) has a complex pathogenesis, and multiple studies have indicated that histone post-translational modifications, especially acetylation, play a significant role in it. With the developme...

Genetic, DNA methylation, and immune profile discrepancies between early-stage single primary lung cancer and synchronous multiple primary lung cancer

Most Recent Articles: Clinical Epigenetics

By: Fenglei Yu， Xiaojie Huang， Danting Zhou， Zhenyu Zhao， Fang Wu， Banglun Qian， Qiang Wang， Juan Chen， Qingchun Liang， Yi Jiang， Qi Ding， Qiongzhi He， Jingqun Tang， Xiang Wang， Wenliang Liu and Chen Chen

7 January 2023 at 08:00

To explore the possible carcinogenesis and help better diagnose and treat patients with synchronous multiple primary lung cancers (sMPLC), we systematically investigated the genetic and DNA methylation profile...

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