Nature, Published online: 25 September 2025; doi:10.1038/d41586-025-03139-9

Preliminary results from a small trial offer the clearest evidence yet that the brain disease’s progression can be slowed.

Nature, Published online: 27 August 2025; doi:10.1038/d41586-025-02647-y

Fresh treatments shift the focus from symptom management to repair, and help children with skin conditions to live active lives.

Nature, Published online: 15 May 2025; doi:10.1038/d41586-025-01518-w

‘Directed’ evolution in the laboratory creates an editing tool that outperforms classic CRISPR systems.

Nature, Published online: 11 June 2024; doi:10.1038/d41586-024-01717-x

The same mRNA technology that quickly brought the world a vaccine for COVID-19 is now showing promise as a bespoke therapy for cancer.

Nature, Published online: 21 March 2024; doi:10.1038/d41586-024-00854-7

The COVID-19 pandemic showed what was possible for gene-based diagnostics. Now comes the true test – economics.

Nature, Published online: 06 December 2023; doi:10.1038/d41586-023-03859-w

Researchers look ahead to the potential uses and benefits of a technology that has been more than 20 years in the making.

Nature, Published online: 04 October 2023; doi:10.1038/d41586-023-03058-7

The commercial success of RNA vaccines for COVID-19 has revved up interest in circular RNAs as the next generation of therapies.

Nature, Published online: 24 May 2023; doi:10.1038/d41586-023-01649-y

Intermediate states show promise as drug targets.

Nature, Published online: 19 December 2022; doi:10.1038/d41586-022-04344-6

The immunotherapy is beginning to show promise in solid tumours, but researchers want more dedicated research in young people.