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Gene body methylation in cancer: molecular mechanisms and clinical applications

Most Recent Articles: Clinical Epigenetics

By: Qi Wang， Fei Xiong， Guanhua Wu， Wenzheng Liu， Junsheng Chen， Bing Wang and Yongjun Chen

28 November 2022 at 08:00

DNA methylation is an important epigenetic mechanism that regulates gene expression. To date, most DNA methylation studies have focussed on CpG islands in the gene promoter region, and the mechanism of methyla...

Hypermethylation of tumor suppressor lncRNA MEF2C-AS1 frequently happened in patients at all stages of colorectal carcinogenesis

Most Recent Articles: Clinical Epigenetics

By: Sangni Qian， Shujuan Lin， Xin Xu， Hao Bai， Aibuta Yeerken， Xiaojiang Ying， Zhenjun Li， Xinglin Fei， Jinhua Yang， Mengling Tang， Jianbing Wang， Mingjuan Jin and Kun Chen

5 September 2022 at 08:00

The novel long noncoding RNA MEF2C-AS1 has been identified to play suppressor roles during tumorigenesis. DNA methylation has a regulatory effect on gene expression in cancer initiation and progression. However, ...