A multiscale drug discovery platform integrating human induced pluripotent stem cells, 3D-engineered heart tissues, and animal models identifies artesunate as a safe and potent antifibrotic compound.

Nature, Published online: 08 May 2024; doi:10.1038/s41586-024-07370-8

Enhanced light–molecule interactions in high-finesse fibre-based Fabry–Pérot microcavities are used to detect and profile individual unlabelled solution-phase biomolecules, leading to potential applications in the life and chemical sciences.

Nature, Published online: 12 July 2023; doi:10.1038/s41586-023-06327-7

Retrotransposons hijack the alternative end-joining DNA repair process of the host for a circularization step to synthesize their second-strand DNA.