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KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid accumulation in pancreatic ductal adenocarcinoma

Cell Death Discovery, Published online: 24 May 2024; doi:10.1038/s41420-024-02020-4

KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid accumulation in pancreatic ductal adenocarcinoma
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Genome-wide characterization of circulating metabolic biomarkers

Nature, Published online: 06 March 2024; doi:10.1038/s41586-024-07148-y

A meta-analysis of genome-wide association studies for 233 circulating metabolites from 33 cohorts reveals more than 400 loci and suggests probable causal genes, providing insights into metabolic pathways and disease aetiology.
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Scientific discovery in the age of artificial intelligence

Nature, Published online: 02 August 2023; doi:10.1038/s41586-023-06221-2

The advances in artificial intelligence over the past decade are examined, with a discussion on how artificial intelligence systems can aid the scientific process and the central issues that remain despite advances.
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