Background: Artificial intelligence-assisted conversational agents have been applied and developed in outpatient departments to improve health services in China. However, there has been little research that evaluates the effect of artificial intelligence-assisted conversational agents on the patient experience related to physicians during outpatient visits. Objective: This aim of this study was to examine whether the use of artificial intelligence-assisted conversational agents improves the patient experience related to physicians during outpatient visits and to further find out the difference in the patient experience between conversational agent users and nonusers. Methods: We used the Chinese Outpatient Experience Questionnaire to survey the patient experience related to physicians during outpatient visits. A sample of 392 adult residents who sought outpatient services from tertiary public hospitals in China was selected by random sampling. The t tests were used to test the mean difference in the patient experience scores between conversational agent users and nonusers. Multiple linear regression analysis was further performed to determine whether the use of artificial intelligence-assisted conversational agents during outpatient visits was associated with a better patient experience related to physicians. Results: Conversational agent user reported significantly higher scores than nonusers in the total patient experience scores (t392=5.589, P<.001 the items and dimensions of physician-patient communication p=".006)," health information short-term outcome general satisfaction multiple linear regression results further showed that after controlling for other factors on participant characteristics use artificial intelligence-assisted conversational agents during outpatient visits significantly influenced total patient experience scores related to physicians averagely increased by conclusions: could improve especially in terms making better accessing more targeted ameliorating outcomes increasing satisfaction. therefore we suggest public hospitals should consider benefits actively deploy departments so as continuously visits.>