Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10464-0

Researchers designed two-component proteins forming quasisymmetric cages via geometric frustration, enabling tunable virus-like assemblies for cargo delivery, cellular uptake and studying intracellular diffusion and protein localization.

Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10554-z

Quasisymmetry could arise from spontaneous symmetry breaking in a system of strongly interacting building blocks with programmed curvatures, and this principle, coupled with a design approach, can generate a rich array of quasisymmetric assemblies.