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Stroke drives glioma progression through the emergence of tumor-associated astrocytes with reduced Ca<sup>2+</sup> activity

Nature Cancer, Published online: 25 September 2026; doi:10.1038/s43018-026-01238-8

Lee and colleagues report that ischemic stroke induces the generation of an astrocytic population that, through reduced calcium signaling, favors the recruitment of tumor-associated macrophages, thereby promoting glioma invasion in preclinical models.
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Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10264-6

Androgen activity in the male embryonic hindbrain prolongs hindbrain differentiation in male individuals and drives sex differences in the incidence and prognosis of posterior fossa type A (PFA) ependymoma, an aggressive childhood brain tumour.
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