arXiv:2609.12422v1 Announce Type: new Abstract: Lux AI Season 3 requires agents to act under partial observability, randomized episode level dynamics, and a best of five match structure that rewards both tactical execution and fast adaptation. We present HORIZON, a hierarchical agent that combines symmetry aware spatial perception, dual memory belief tracking, relic centric graph attention, information gain driven exploration, and an opponent conditioned policy mixture. HORIZON separates short horizon control from cross match meta reasoning, while auxiliary belief and world model objectives stabilize learning. Trained with PPO in a large scale JAX simulator, the resulting agent explicitly infers hidden game parameters and opponent style. Experiments show consistent gains in match win rate, episode win rate, adaptation gain, and league rating over strong recurrent and feed forward baselines.

arXiv:2605.26074v1 Announce Type: cross Abstract: Existing financial NLP benchmarks often rely on labels supplied by outside observers, measuring how language is perceived rather than what speakers have committed to in the market. We introduce StakeBench, an evaluation framework for language understanding grounded in market commitment. StakeBench links 560,876 comments from 2,261 resolved markets to verified position, action, and market-odds records across Polymarket and Manifold. Supervision is derived from observable market behavior. Position sides, post-comment trading actions, and market-odds trajectories replace human annotation. Four diagnostic tasks test whether models detect market commitment, identify the revealed side, anticipate future action, and perform collective odds projection. Three commitment-aware metrics measure alignment with revealed preferences rather than perceived sentiment. Validity audits and explicit interpretation boundaries help distinguish observable commitment signals from latent belief and causal market-odds impact. Across 15 LLMs and 18 topics and platform settings, models partially recover position-side signals, with Directed Accuracy from 0.506 to 0.599, but show structural failures on later tasks. Ten of the fifteen models collapse to one or two action labels in future action anticipation, and no model consistently improves on the naive odds-direction baseline in collective odds projection. Model scale is not correlated with performance, finance-domain tuning does not improve revealed-side identification, and platform incentives strongly shape higher-order results. StakeBench is packaged with evaluation code and dataset under CC-BY 4.0.

Xiao et al. identify α-KG as a rosacea-associated metabolite that activates the OXGR1-Gq-MYL9 axis in the vascular smooth muscle cells to boost contractility and suppress pathological vasodilation underlying erythema. Cryo-EM reveals a bipartite-acid pocket of OXGR1 that enables structure-guided development of A-1, a selective agonist that alleviates erythema in rosacea-like models.

Nature, Published online: 16 March 2026; doi:10.1038/s41586-026-10372-3

Direct conversion from alkenes to alkynes

arXiv:2602.13949v1 Announce Type: cross Abstract: Reinforcement learning has become the central approach for language models (LMs) to learn from environmental reward or feedback. In practice, the environmental feedback is usually sparse and delayed. Learning from such signals is challenging, as LMs must implicitly infer how observed failures should translate into behavioral changes for future iterations. We introduce Experiential Reinforcement Learning (ERL), a training paradigm that embeds an explicit experience-reflection-consolidation loop into the reinforcement learning process. Given a task, the model generates an initial attempt, receives environmental feedback, and produces a reflection that guides a refined second attempt, whose success is reinforced and internalized into the base policy. This process converts feedback into structured behavioral revision, improving exploration and stabilizing optimization while preserving gains at deployment without additional inference cost. Across sparse-reward control environments and agentic reasoning benchmarks, ERL consistently improves learning efficiency and final performance over strong reinforcement learning baselines, achieving gains of up to +81% in complex multi-step environments and up to +11% in tool-using reasoning tasks. These results suggest that integrating explicit self-reflection into policy training provides a practical mechanism for transforming feedback into durable behavioral improvement.