arXiv:2605.24399v1 Announce Type: new Abstract: Healthcare models are transitioning from unimodal prediction toward multimodal reasoning over heterogeneous diagnostic inputs. In computational pathology, for complex tumor subtypes where morphology alone can be challenging to distinguish, pathology reports and molecular measurements may provide additional diagnostic evidence alongside whole-slide images, yet existing models often fail to clarify how diverse signals assemble into recognizable diagnostic concepts. We propose ConceptM$^3$oE (Concept Multimodal MoE), which embeds concept formation directly within interaction-aware mixture-of-experts (MoE) pathways. The architecture decomposes evidence into modality-specific, redundant, and synergistic experts, which are then projected into structured concept bottlenecks mapping latent features to a hierarchy of morphology and biomarker concepts. To prevent the information loss typical of interpretable bottlenecks, we utilize residual pathways within each expert to allow task-relevant signals to flow both through the concepts and directly to the final task prediction, so that high performance is maintained alongside interpretability. Across an institutional pediatric brain tumor cohort and a public glioma cohort, the framework delivers competitive performance to unconstrained models while producing reasoning traces validated by an independent neuropathologist. In data-limited regimes, ConceptM$^3$oE improves limited-data performance, increasing macro-F1 from 56.41% to 66.70% at small training sizes compared to non-concept-informed baselines, while also showing faster training convergence consistent with the regularizing effect of concept learning. This work offers a scalable path toward high-performance medical AI that is inherently verifiable and better aligned with the complex decision-making of clinical practice.

arXiv:2504.04717v5 Announce Type: replace-cross Abstract: Recent advances in large language models (LLMs) have substantially improved single-turn task performance, yet real-world applications increasingly demand sophisticated multi-turn interactions. This survey provides a comprehensive review of recent progress in evaluating and enhancing multi-turn LLM interactions. Centered on a task-oriented taxonomy-spanning instruction following in domains such as mathematics and coding, and conversational engagement in role-playing, healthcare, education, and adversarial jailbreak settings-we systematically examine the challenges of maintaining context, coherence, fairness, and responsiveness across prolonged dialogues. We organize existing benchmarks and datasets into coherent categories reflecting the evolving landscape of multi-turn dialogue evaluation, and review a broad spectrum of enhancement methodologies, including model-centric strategies (in-context learning, supervised fine-tuning, reinforcement learning, and architectural innovations), external integration approaches (memory augmentation, retrieval-based methods, and knowledge graphs), and agent-based techniques for collaborative interaction. Finally, we identify open challenges and promising directions for future research to further improve the robustness and effectiveness of multi-turn LLM interactions.