❌

Reading view

Safe to Stop? Risk-Constrained Stopping for Sequential Clinical Diagnosis Agents

arXiv:2609.09678v1 Announce Type: new Abstract: Clinical diagnosis agents must decide not only what test to request next, but also when to diagnose or defer. Existing agent benchmarks largely evaluate accuracy after fixed or unconstrained interaction, leaving autonomous stopping reliability implicit. We present Cros, a risk-constrained stopping layer combining state-wise error ranking, policy design on disjoint development splits, and LTT-style exact tests of selective diagnostic error and minimum autonomous coverage for complete sequential policies. Its finite-sample guarantee requires the candidate family, testing rule, and any randomization to be frozen before calibration labels are accessed. On a 1,834-episode MIMIC-derived abdominal-pain benchmark, the full ranker achieves exploratory state-error AUROC 0.853, compared with 0.715 for maximum class probability and 0.552 for the backbone's native stop score. On the previously viewed 367-episode evaluation split, analytically averaging over the frozen Cros weights yields 16.9% selective error at 78.8% coverage, cost 5.57, and 0.68 tests, versus 30.8% error at 100% coverage, cost 8.14, and 1.53 tests under native stopping. Forced continuation is non-monotone: error is 28.3% with HPI alone and 34.3% after full workup. However, the uniform-weight mixture ablation is cheaper on this viewed split despite missing the locked development margins, and Cros nominally satisfies the joint criterion in only 6 of 20 development resplits. Because evaluation labels were inspected during earlier development, these findings provide exploratory feasibility and audit evidence, not a confirmatory safety certificate.
  •  

Which Medical Questions Deserve Rationales? Perturbation-Sensitive Selection for Robust QA

arXiv:2609.09684v1 Announce Type: cross Abstract: Medical question-answering datasets often contain answer labels, whereas high-quality rationales remain scarce, noisy, or costly to validate. This changes the acquisition question: rather than asking which questions should be labeled, we ask which already-labeled questions should receive rationale supervision under a fixed token budget. We study an offline version of this problem in which candidate rationales are visible to the selector but withheld from downstream training unless selected. We propose root-mean-square Robustness-based Sample Prioritization (RMS-RSP), which perturbs hidden states only at rationale tokens and measures the resulting shift in the gold-versus-best-distractor margin. Across five medical QA datasets, MedGemma-4B-IT, three training seeds, ten budgeted non-RSP selectors, and an unbudgeted full-supervision reference, RMS-RSP provides a deliberately qualified result. Its locked-budget accuracy is 60.61% on average versus 60.08% for Random, with a statistically resolved gain only on AfriMed-QA (+1.44 points). Its full-budget accuracy area is not better than Random. However, after three answer-option reorderings, RMS-RSP improves robust accuracy and semantic consistency by 1.91 and 2.85 points on average, respectively, with the same direction on all five datasets. Training on every pool rationale raises macro accuracy to 63.74%, but consumes 29--254 times more rationale tokens and does not uniformly improve robustness. These findings do not establish universal accuracy gains; they instead suggest that rationale-local boundary sensitivity can identify supervision that improves invariance to semantically equivalent formatting changes.
  •  
❌