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Neuro-Symbolic Decoding of Neural Activity

arXiv:2603.03343v1 Announce Type: new Abstract: We propose NEURONA, a neuro-symbolic framework for fMRI decoding and concept grounding in neural activity. Leveraging image- and video-based fMRI question-answering datasets, NEURONA learns to decode interacting concepts from visual stimuli based on patterns of fMRI responses, integrating symbolic reasoning and compositional execution with fMRI grounding across brain regions. We demonstrate that incorporating structural priors (e.g., compositional predicate-argument dependencies between concepts) into the decoding process significantly improves both decoding accuracy over precise queries, and notably, generalization to unseen queries at test time. With NEURONA, we highlight neuro-symbolic frameworks as promising tools for understanding neural activity.
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On the Equivalence of Random Network Distillation, Deep Ensembles, and Bayesian Inference

arXiv:2602.19964v1 Announce Type: cross Abstract: Uncertainty quantification is central to safe and efficient deployments of deep learning models, yet many computationally practical methods lack lacking rigorous theoretical motivation. Random network distillation (RND) is a lightweight technique that measures novelty via prediction errors against a fixed random target. While empirically effective, it has remained unclear what uncertainties RND measures and how its estimates relate to other approaches, e.g. Bayesian inference or deep ensembles. This paper establishes these missing theoretical connections by analyzing RND within the neural tangent kernel framework in the limit of infinite network width. Our analysis reveals two central findings in this limit: (1) The uncertainty signal from RND -- its squared self-predictive error -- is equivalent to the predictive variance of a deep ensemble. (2) By constructing a specific RND target function, we show that the RND error distribution can be made to mirror the centered posterior predictive distribution of Bayesian inference with wide neural networks. Based on this equivalence, we moreover devise a posterior sampling algorithm that generates i.i.d. samples from an exact Bayesian posterior predictive distribution using this modified \textit{Bayesian RND} model. Collectively, our findings provide a unified theoretical perspective that places RND within the principled frameworks of deep ensembles and Bayesian inference, and offer new avenues for efficient yet theoretically grounded uncertainty quantification methods.
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It Takes a Good Model to Train a Good Model: Generalized Gaussian Priors for Optimized LLMs

arXiv:2506.00486v4 Announce Type: replace-cross Abstract: Despite rapid progress in large language models (LLMs), the statistical structure of their weights, activations, and gradients-and its implications for initialization, training dynamics, and efficiency-remains largely unexplored. We empirically show that these quantities in LLMs are well modeled by generalized Gaussian (GG) distributions, and introduce a unified, end-to-end optimization framework grounded in this observation. Our contributions are threefold: (1) a GG-based initialization that aligns with trained model statistics, accelerating convergence and improving accuracy; (2) ACT, a progressive activation-constrained training method that reduces redundancy and propagation overhead; and (3) GCT, a gradient-constrained training algorithm that substantially lowers communication cost in distributed training. Experiments across diverse architectures demonstrate consistently smaller, faster models with minimal communication overhead that match or surpass standard baselines. By anchoring LLM optimization in principled statistical modeling, this work advances efficient, scalable, and hardware-aware AI systems.
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MoMaGen: Generating Demonstrations under Soft and Hard Constraints for Multi-Step Bimanual Mobile Manipulation

arXiv:2510.18316v2 Announce Type: replace-cross Abstract: Imitation learning from large-scale, diverse human demonstrations has been shown to be effective for training robots, but collecting such data is costly and time-consuming. This challenge intensifies for multi-step bimanual mobile manipulation, where humans must teleoperate both the mobile base and two high-DoF arms. Prior X-Gen works have developed automated data generation frameworks for static (bimanual) manipulation tasks, augmenting a few human demos in simulation with novel scene configurations to synthesize large-scale datasets. However, prior works fall short for bimanual mobile manipulation tasks for two major reasons: 1) a mobile base introduces the problem of how to place the robot base to enable downstream manipulation (reachability) and 2) an active camera introduces the problem of how to position the camera to generate data for a visuomotor policy (visibility). To address these challenges, MoMaGen formulates data generation as a constrained optimization problem that satisfies hard constraints (e.g., reachability) while balancing soft constraints (e.g., visibility while navigation). This formulation generalizes across most existing automated data generation approaches and offers a principled foundation for developing future methods. We evaluate on four multi-step bimanual mobile manipulation tasks and find that MoMaGen enables the generation of much more diverse datasets than previous methods. As a result of the dataset diversity, we also show that the data generated by MoMaGen can be used to train successful imitation learning policies using a single source demo. Furthermore, the trained policy can be fine-tuned with a very small amount of real-world data (40 demos) to be succesfully deployed on real robotic hardware. More details are on our project page: momagen.github.io.
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AI-driven Large-scale Electron Microscopy enables Whole-tissue Subcellular Digitization

arXiv:2511.02860v2 Announce Type: replace-cross Abstract: The distribution and interactions of cellular organelles play a critical role in mediating cellular physiology and pathology. Large-scale electron microscopy enables visualization of organelle distribution and interactions at the tissue level with nanometer resolution, but robust and efficient computational analysis tools are lacking. Here, we present a deep learning tool for universal large-scale 2D/3D electron microscopy analysis, DeepOrganelle. This new tool enables high-throughput, cell-resolved spatiotemporal mapping and digitization of organelle distribution and interactions. When applied to spermatogenesis across 12 stages and 22 differentiation status of the germ cells, DeepOrganelle uncovered previously unrecognized, stage-dependent dynamics of mitochondria-endoplasmic reticulum contact sites within one subphase of prophase I during meiosis. It also revealed coordinated organelle redistribution in Sertoli cells towards the blood-testis barrier, digitizing the remodeling dynamics of the tissue. This study demonstrates that DeepOrganelle provides a powerful framework that captures subcellular dynamics at the whole-tissue level.
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