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Adaptive Multi-Agent Reasoning for Text-to-Video Retrieval

arXiv:2602.19040v1 Announce Type: cross Abstract: The rise of short-form video platforms and the emergence of multimodal large language models (MLLMs) have amplified the need for scalable, effective, zero-shot text-to-video retrieval systems. While recent advances in large-scale pretraining have improved zero-shot cross-modal alignment, existing methods still struggle with query-dependent temporal reasoning, limiting their effectiveness on complex queries involving temporal, logical, or causal relationships. To address these limitations, we propose an adaptive multi-agent retrieval framework that dynamically orchestrates specialized agents over multiple reasoning iterations based on the demands of each query. The framework includes: (1) a retrieval agent for scalable retrieval over large video corpora, (2) a reasoning agent for zero-shot contextual temporal reasoning, and (3) a query reformulation agent for refining ambiguous queries and recovering performance for those that degrade over iterations. These agents are dynamically coordinated by an orchestration agent, which leverages intermediate feedback and reasoning outcomes to guide execution. We also introduce a novel communication mechanism that incorporates retrieval-performance memory and historical reasoning traces to improve coordination and decision-making. Experiments on three TRECVid benchmarks spanning eight years show that our framework achieves a twofold improvement over CLIP4Clip and significantly outperforms state-of-the-art methods by a large margin.
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AI-driven Large-scale Electron Microscopy enables Whole-tissue Subcellular Digitization

arXiv:2511.02860v2 Announce Type: replace-cross Abstract: The distribution and interactions of cellular organelles play a critical role in mediating cellular physiology and pathology. Large-scale electron microscopy enables visualization of organelle distribution and interactions at the tissue level with nanometer resolution, but robust and efficient computational analysis tools are lacking. Here, we present a deep learning tool for universal large-scale 2D/3D electron microscopy analysis, DeepOrganelle. This new tool enables high-throughput, cell-resolved spatiotemporal mapping and digitization of organelle distribution and interactions. When applied to spermatogenesis across 12 stages and 22 differentiation status of the germ cells, DeepOrganelle uncovered previously unrecognized, stage-dependent dynamics of mitochondria-endoplasmic reticulum contact sites within one subphase of prophase I during meiosis. It also revealed coordinated organelle redistribution in Sertoli cells towards the blood-testis barrier, digitizing the remodeling dynamics of the tissue. This study demonstrates that DeepOrganelle provides a powerful framework that captures subcellular dynamics at the whole-tissue level.
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