arXiv:2603.26535v2 Announce Type: replace Abstract: We propose Process-Aware Policy Optimization (PAPO), a method that integrates process-level evaluation into Group Relative Policy Optimization (GRPO) through decoupled advantage normalization, to address two limitations of existing reward designs. Outcome reward models (ORM) evaluate only final-answer correctness, treating all correct responses identically regardless of reasoning quality, and gradually lose the advantage signal as groups become uniformly correct. Process reward models (PRM) offer richer supervision, but directly using PRM scores causes reward hacking, where models exploit verbosity to inflate scores while accuracy collapses. PAPO resolves both by composing the advantage from an outcome component Aout, derived from ORM and normalized over all responses, and a process component Aproc, derived from a rubric-based PRM and normalized exclusively among correct responses. This decoupled design ensures that Aout anchors training on correctness while Aproc differentiates reasoning quality without distorting the outcome signal. Experiments across multiple model scales and six benchmarks demonstrate that PAPO consistently outperforms ORM, reaching 51.3% vs.\ 46.3% on OlympiadBench while continuing to improve as ORM plateaus and declines.

arXiv:2601.06810v2 Announce Type: replace-cross Abstract: The Wasserstein-Fisher-Rao (WFR) metric extends dynamic optimal transport (OT) by coupling displacement with change of mass, providing a principled geometry for modeling unbalanced snapshot dynamics. Existing WFR solvers, however, are often unstable, computationally expensive, and difficult to scale. Here we introduce WFR Flow Matching (WFR-FM), a simulation-free training algorithm that unifies flow matching with dynamic unbalanced OT. Unlike classical flow matching which regresses only a transport vector field, WFR-FM simultaneously regresses a vector field for displacement and a scalar growth rate function for birth-death dynamics, yielding continuous flows under the WFR geometry. Theoretically, we show that minimizing the WFR-FM loss exactly recovers WFR geodesics. Empirically, WFR-FM yields more accurate and robust trajectory inference in single-cell biology, reconstructing consistent dynamics with proliferation and apoptosis, estimating time-varying growth fields, and applying to generative dynamics under imbalanced data. It outperforms state-of-the-art baselines in efficiency, stability, and reconstruction accuracy. Overall, WFR-FM establishes a unified and efficient paradigm for learning dynamical systems from unbalanced snapshots, where not only states but also mass evolve over time. The Python code is available at https://github.com/QiangweiPeng/WFR-FM.

arXiv:2603.29520v1 Announce Type: cross Abstract: Encrypted traffic classification is a critical task for network security. While deep learning has advanced this field, the occlusion of payload semantics by encryption severely challenges standard modeling approaches. Most existing frameworks rely on static and homogeneous pipelines that apply uniform parameter sharing and static fusion strategies across all inputs. This one-size-fits-all static design is inherently flawed: by forcing structured headers and randomized payloads into a unified processing pipeline, it inevitably entangles the raw protocol signals with stochastic encryption noise, thereby degrading the fine-grained discriminative features. In this paper, we propose TrafficMoE, a framework that breaks through the bottleneck of static modeling by establishing a Disentangle-Filter-Aggregate (DFA) paradigm. Specifically, to resolve the structural between-components conflict, the architecture disentangles headers and payloads using dual-branch sparse Mixture-of-Experts (MoE), enabling modality-specific modeling. To mitigate the impact of stochastic noise, an uncertainty-aware filtering mechanism is introduced to quantify reliability and selectively suppress high-variance representations. Finally, to overcome the limitations of static fusion, a routing-guided strategy aggregates cross-modality features dynamically, that adaptively weighs contributions based on traffic context. With this DFA paradigm, TrafficMoE maximizes representational efficiency by focusing solely on the most discriminative traffic features. Extensive experiments on six datasets demonstrate TrafficMoE consistently outperforms state-of-the-art methods, validating the necessity of heterogeneity-aware modeling in encrypted traffic analysis. The source code is publicly available at https://github.com/Posuly/TrafficMoE_main.

arXiv:2603.29537v1 Announce Type: cross Abstract: Network traffic classification using self-supervised pre-training models based on Masked Autoencoders (MAE) has demonstrated a huge potential. However, existing methods are confined to isolated byte-level reconstruction of individual flows, lacking adequate perception of the multi-granularity contextual relationship in traffic. To address this limitation, we propose Mean MAE (MMAE), a teacher-student MAE paradigm with flow mixing strategy for building encrypted traffic pre-training model. MMAE employs a self-distillation mechanism for teacher-student interaction, where the teacher provides unmasked flow-level semantic supervision to advance the student from local byte reconstruction to multi-granularity comprehension. To break the information bottleneck in individual flows, we introduce a dynamic Flow Mixing (FlowMix) strategy to replace traditional random masking mechanism. By constructing challenging cross-flow mixed samples with interferences, it compels the model to learn discriminative representations from distorted tokens. Furthermore, we design a Packet-importance aware Mask Predictor (PMP) equipped with an attention bias mechanism that leverages packet-level side-channel statistics to dynamically mask tokens with high semantic density. Numerous experiments on a number of datasets covering encrypted applications, malware, and attack traffic demonstrate that MMAE achieves state-of-the-art performance. The code is available at https://github.com/lx6c78/MMAE

arXiv:2603.28325v2 Announce Type: replace-cross Abstract: Biomedical knowledge resources often either preserve evidence as unstructured text or compress it into flat triples that omit study design, provenance, and quantitative support. Here we present EvidenceNet, a framework and dataset for building disease-specific knowledge graphs from full-text biomedical literature. EvidenceNet uses a large language model (LLM)-assisted pipeline to extract experimentally grounded findings as structured evidence nodes, normalize biomedical entities, score evidence quality, and connect evidence records through typed semantic relations. We release two resources: EvidenceNet-HCC with 7,872 evidence records, 10,328 graph nodes, and 49,756 edges, and EvidenceNet-CRC with 6,622 records, 8,795 nodes, and 39,361 edges. Technical validation shows high component fidelity, including 98.3% field-level extraction accuracy, 100.0% high-confidence entity-link accuracy, 87.5% fusion integrity, and 90.0% semantic relation-type accuracy. In downstream evaluation, EvidenceNet improves internal and external retrieval-augmented question answering and retains structural signal for future link prediction and target prioritization. These results establish EvidenceNet as a disease-specific resource for evidence-aware biomedical reasoning and hypothesis generation.

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10264-6

Androgen activity in the male embryonic hindbrain prolongs hindbrain differentiation in male individuals and drives sex differences in the incidence and prognosis of posterior fossa type A (PFA) ependymoma, an aggressive childhood brain tumour.

Human-specific transcriptomic and regulatory features are present in the cerebellum, with ZP2 playing a key role in synapse regulation. ZP2 expression is induced by pontine mossy fibers, leading to decreased synaptic proteins and neuronal activity, which provides insights into the evolutionary development of the human cerebellum.

arXiv:2603.07413v1 Announce Type: cross Abstract: The Internet of Underwater Things (IoUT) is becoming a critical infrastructure for ocean observation, marine resource management, and climate science. Its development is hindered by severe acoustic attenuation, propagation delays far exceeding those of terrestrial wireless systems, strict energy constraints, and dynamic topologies shaped by ocean currents. Machine learning (ML) has emerged as a key enabler for addressing these limitations, offering data driven mechanisms that enhance performance across all layers of underwater wireless sensor networks. This tutorial survey synthesises ML methodologies supervised, unsupervised, reinforcement, and deep learning specifically contextualised for underwater communication environments. It outlines the algorithmic principles of each paradigm and examines the conditions under which particular approaches deliver superior performance. A layer wise analysis highlights physical layer gains in localisation and channel estimation, MAC layer adaptations that improve channel utilisation, network layer routing strategies that extend operational lifetime, and transport layer mechanisms capable of reducing packet loss by up to 91 percent. At the application layer, ML enables substantial data compression and object detection accuracies reaching 92 percent. Drawing on 300 studies from 2012 to 2025, the survey documents energy efficiency gains of 7 to 29 times, throughput improvements over traditional protocols, and cross layer optimisation benefits of up to 42 percent. It also identifies persistent barriers, including limited datasets, computational constraints, and the gap between theoretical models and real world deployment. The survey concludes with emerging research directions and a technology roadmap supporting ML adoption in operational underwater networks.

arXiv:2603.07496v1 Announce Type: cross Abstract: Artificial Intelligence (AI) agents have evolved from passive predictive tools into active entities capable of autonomous decision-making and environmental interaction, driven by the reasoning capabilities of Large Language Models (LLMs). However, this evolution has introduced critical security vulnerabilities that existing frameworks fail to address. The Hierarchical Autonomy Evolution (HAE) framework organizes agent security into three tiers: Cognitive Autonomy (L1) targets internal reasoning integrity; Execution Autonomy (L2) covers tool-mediated environmental interaction; Collective Autonomy (L3) addresses systemic risks in multi-agent ecosystems. We present a taxonomy of threats spanning cognitive manipulation, physical environment disruption, and multi-agent systemic failures, and evaluate existing defenses while identifying key research gaps. The findings aim to guide the development of multilayered, autonomy-aware defense architectures for trustworthy AI agent systems.

arXiv:2603.08572v1 Announce Type: cross Abstract: Learning natural, stable, and compositionally generalizable whole-body control policies for humanoid robots performing simultaneous locomotion and manipulation (loco-manipulation) remains a fundamental challenge in robotics. Existing reinforcement learning approaches typically rely on a single monolithic policy to acquire multiple skills, which often leads to cross-skill gradient interference and motion pattern conflicts in high-degree-of-freedom systems. As a result, generated behaviors frequently exhibit unnatural movements, limited stability, and poor generalization to complex task compositions. To address these limitations, we propose MetaWorld-X, a hierarchical world model framework for humanoid control. Guided by a divide-and-conquer principle, our method decomposes complex control problems into a set of specialized expert policies (Specialized Expert Policies, SEP). Each expert is trained under human motion priors through imitation-constrained reinforcement learning, introducing biomechanically consistent inductive biases that ensure natural and physically plausible motion generation. Building upon this foundation, we further develop an Intelligent Routing Mechanism (IRM) supervised by a Vision-Language Model (VLM), enabling semantic-driven expert composition. The VLM-guided router dynamically integrates expert policies according to high-level task semantics, facilitating compositional generalization and adaptive execution in multi-stage loco-manipulation tasks.

arXiv:2509.14980v2 Announce Type: replace-cross Abstract: Mobile manipulation requires the coordinated control of a mobile base and a robotic arm while simultaneously perceiving both global scene context and fine-grained object details. Existing single-view approaches often fail in unstructured environments due to limited fields of view, exploration, and generalization abilities. Moreover, classical controllers, although stable, struggle with efficiency and manipulability near singularities. To address these challenges, we propose M4Diffuser, a hybrid framework that integrates a Multi-View Diffusion Policy with a novel Reduced and Manipulability-aware QP (ReM-QP) controller for mobile manipulation. The diffusion policy leverages proprioceptive states and complementary camera perspectives with both close-range object details and global scene context to generate task-relevant end-effector goals in the world frame. These high-level goals are then executed by the ReM-QP controller, which eliminates slack variables for computational efficiency and incorporates manipulability-aware preferences for robustness near singularities. Comprehensive experiments in simulation and real-world environments show that M4Diffuser achieves 7 to 56 percent higher success rates and reduces collisions by 3 to 31 percent over baselines. Our approach demonstrates robust performance for smooth whole-body coordination, and strong generalization to unseen tasks, paving the way for reliable mobile manipulation in unstructured environments. Details of the demo and supplemental material are available on our project website https://sites.google.com/view/m4diffuser.

arXiv:2507.15518v4 Announce Type: replace Abstract: Creating an immersive and interactive theatrical experience is a long-term goal in the field of interactive narrative. The emergence of large language models (LLMs) provides a new path to achieve this goal. However, existing LLM-based drama generation methods often produce models that lack initiative and cannot interact with the physical scene, while typically requiring detailed user input that diminishes the immersion of live performance. To address these challenges, we propose HAMLET, a hierarchical adaptive multi-agent framework focused on drama creation and real-time online performance. Given a simple topic, the framework first generates a narrative blueprint to guide the subsequent improvisational performance. In the online performance phase, each actor is equipped with an adaptive reasoning module that enables decision-making based on their personas, memories, goals, and emotional states during complex group chat scenarios. Beyond dialogue, actor agents engage in embodied interactions by changing the state of scene props through actions such as opening a letter or picking up a weapon, which are broadcast to update the global environmental context. To objectively assess the quality of live embodied theatrics, we establish a comprehensive evaluation method and introduce HAMLETJudge, a specialized critic model for automated evaluation. Experimental results demonstrate that HAMLET excels in creating expressive, coherent, and physically interactive theatrical experiences in an autonomous manner.

arXiv:2602.14042v1 Announce Type: cross Abstract: In real-world scenarios, the performance of semantic segmentation often deteriorates when processing low-quality (LQ) images, which may lack clear semantic structures and high-frequency details. Although image restoration techniques offer a promising direction for enhancing degraded visual content, conventional real-world image restoration (Real-IR) models primarily focus on pixel-level fidelity and often fail to recover task-relevant semantic cues, limiting their effectiveness when directly applied to downstream vision tasks. Conversely, existing segmentation models trained on high-quality data lack robustness under real-world degradations. In this paper, we propose Restoration Adaptation for Semantic Segmentation (RASS), which effectively integrates semantic image restoration into the segmentation process, enabling high-quality semantic segmentation on the LQ images directly. Specifically, we first propose a Semantic-Constrained Restoration (SCR) model, which injects segmentation priors into the restoration model by aligning its cross-attention maps with segmentation masks, encouraging semantically faithful image reconstruction. Then, RASS transfers semantic restoration knowledge into segmentation through LoRA-based module merging and task-specific fine-tuning, thereby enhancing the model's robustness to LQ images. To validate the effectiveness of our framework, we construct a real-world LQ image segmentation dataset with high-quality annotations, and conduct extensive experiments on both synthetic and real-world LQ benchmarks. The results show that SCR and RASS significantly outperform state-of-the-art methods in segmentation and restoration tasks. Code, models, and datasets will be available at https://github.com/Ka1Guan/RASS.git.