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Safety-Aligned 3D Object Detection: Single-Vehicle, Cooperative, and End-to-End Perspectives

arXiv:2604.03325v1 Announce Type: cross Abstract: Perception plays a central role in connected and autonomous vehicles (CAVs), underpinning not only conventional modular driving stacks, but also cooperative perception systems and recent end-to-end driving models. While deep learning has greatly improved perception performance, its statistical nature makes perfect predictions difficult to attain. Meanwhile, standard training objectives and evaluation benchmarks treat all perception errors equally, even though only a subset is safety-critical. In this paper, we investigate safety-aligned evaluation and optimization for 3D object detection that explicitly characterize high-impact errors. Building on our previously proposed safety-oriented metric, NDS-USC, and safety-aware loss function, EC-IoU, we make three contributions. First, we present an expanded study of single-vehicle 3D object detection models across diverse neural network architectures and sensing modalities, showing that gains under standard metrics such as mAP and NDS may not translate to safety-oriented criteria represented by NDS-USC. With EC-IoU, we reaffirm the benefit of safety-aware fine-tuning for improving safety-critical detection performance. Second, we conduct an ego-centric, safety-oriented evaluation of AV-infrastructure cooperative object detection models, underscoring its superiority over vehicle-only models and demonstrating a safety impact analysis that illustrates the potential contribution of cooperative models to "Vision Zero." Third, we integrate EC-IoU into SparseDrive and show that safety-aware perception hardening can reduce collision rate by nearly 30% and improve system-level safety directly in an end-to-end perception-to-planning framework. Overall, our results indicate that safety-aligned perception evaluation and optimization offer a practical path toward enhancing CAV safety across single-vehicle, cooperative, and end-to-end autonomy settings.
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RDEx-CMOP: Feasibility-Aware Indicator-Guided Differential Evolution for Fixed-Budget Constrained Multiobjective Optimization

arXiv:2604.03708v1 Announce Type: cross Abstract: Constrained multiobjective optimisation requires fast feasibility attainment together with stable convergence and diversity preservation under strict evaluation budgets. This report documents RDEx-CMOP, the differential evolution variant used in the IEEE CEC 2025 numerical optimisation competition (C06 special session) constrained multiobjective track. RDEx-CMOP integrates an {\epsilon}-level feasibility schedule, a SPEA2-style indicator-driven fitness assignment, and a fitness-oriented current-to-pbest/1 mutation operator. We evaluate RDEx-CMOP on the official CEC 2025 CMOP benchmark using the median-target U-score framework and the released trace data. Experimental results show that RDEx-CMOP achieves the highest total score and the best overall average rank among all released comparison algorithms, with strong target-attainment behaviour and near-zero final violation on most problems.
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StableTTA: Training-Free Test-Time Adaptation that Improves Model Accuracy on ImageNet1K to 96%

arXiv:2604.04552v1 Announce Type: cross Abstract: Ensemble methods are widely used to improve predictive performance, but their effectiveness often comes at the cost of increased memory usage and computational complexity. In this paper, we identify a conflict in aggregation strategies that negatively impacts prediction stability. We propose StableTTA, a training-free method to improve aggregation stability and efficiency. Empirical results on ImageNet-1K show gains of 10.93--32.82\% in top-1 accuracy, with 33 models achieving over 95\% accuracy and several surpassing 96\%. Notably, StableTTA allows lightweight architectures to outperform ViT by 11.75\% in top-1 accuracy while using less than 5\% of parameters and reducing computational cost by approximately 89.1\% (in GFLOPs), enabling high-accuracy inference on resource-constrained devices.
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XModBench: Benchmarking Cross-Modal Capabilities and Consistency in Omni-Language Models

arXiv:2510.15148v2 Announce Type: replace-cross Abstract: Omni-modal large language models (OLLMs) aim to unify audio, vision, and text understanding within a single framework. While existing benchmarks primarily evaluate general cross-modal question-answering ability, it remains unclear whether OLLMs achieve modality-invariant reasoning or exhibit modality-specific biases. We introduce XModBench, a large-scale tri-modal benchmark explicitly designed to measure cross-modal consistency. XModBench comprises 60,828 multiple-choice questions spanning five task families and systematically covers all six modality compositions in question-answer pairs, enabling fine-grained diagnosis of an OLLM's modality-invariant reasoning, modality disparity, and directional imbalance. Experiments show that even the strongest model, Gemini 2.5 Pro, (i) struggles with spatial and temporal reasoning, achieving less than 60% accuracy, (ii) reveals persistent modality disparities, with performance dropping substantially when the same semantic content is conveyed through audio rather than text, and (iii) shows systematic directional imbalance, exhibiting lower consistency when vision serves as context compared to text. These findings indicate that current OLLMs remain far from truly modality-invariant reasoning and position XModBench as a fundamental diagnostic tool for evaluating and improving cross-modal competence. All data and evaluation tools will be available at https://xingruiwang.github.io/projects/XModBench/.
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ContextDrag: Precise Drag-Based Image Editing via Context-Preserving Token Injection and Position-Aligned Attention

arXiv:2512.08477v2 Announce Type: replace-cross Abstract: Drag-based image editing enables intuitive visual manipulation through point-based drag operations. Existing methods mainly rely on diffusion inversion or pixel-space warping with inpainting. However, inversion inherently introduces approximation errors that degrade texture fidelity, whereas rigid pixel-space operations discard semantic context and produce unnatural deformations. To address these issues, we introduce ContextDrag, to our knowledge the first framework that brings drag-based manipulation into the in-context image editing paradigm. By leveraging the in-context capabilities of editing models (e.g., FLUX-Kontext), ContextDrag enables precise drag editing without inversion or fine-tuning. Specifically, we first propose Context-preserving Token Injection (CTI), which injects VAE-encoded reference features into attention layers at spatially aligned target positions, guided by latent-space correspondences estimated directly from user-specified control points. By operating on clean, directly encoded features rather than noisy inversion outputs, CTI preserves rich texture details and enables precise drag control. Second, we propose Position-Aligned Attention (PAA) to eliminate interference caused by spatial displacement of reference features. PAA re-encodes positional embeddings of displaced reference tokens to match their target locations, and masks overlapping regions between source and destination to prevent conflicting features from degrading visual consistency. Experiments on DragBench-SR and DragBench-DR demonstrate that ContextDrag achieves SOTA editing accuracy and overall quality, and comprehensive ablations validate the effectiveness of each proposed component. Code will be publicly available.
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RASA: Routing-Aware Safety Alignment for Mixture-of-Experts Models

arXiv:2602.04448v2 Announce Type: replace-cross Abstract: Mixture-of-Experts (MoE) language models introduce unique challenges for safety alignment due to their sparse routing mechanisms, which can enable degenerate optimization behaviors under standard full-parameter fine-tuning. In our preliminary experiments, we observe that naively applying full-parameter safety fine-tuning to MoE models can reduce attack success rates through routing or expert dominance effects, rather than by directly repairing Safety-Critical Experts. To address this challenge, we propose RASA, a routing-aware expert-level alignment framework that explicitly repairs Safety-Critical Experts while preventing routing-based bypasses. RASA identifies experts disproportionately activated by successful jailbreaks, selectively fine-tunes only these experts under fixed routing, and subsequently enforces routing consistency with safety-aligned contexts. Across two representative MoE architectures and a diverse set of jailbreak attacks, RASA achieves near-perfect robustness, strong cross-attack generalization, and substantially reduced over-refusal, while preserving general capabilities on benchmarks such as MMLU, GSM8K, and TruthfulQA. Our results suggest that robust MoE safety alignment benefits from targeted expert repair rather than global parameter updates, offering a practical and architecture-preserving alternative to prior approaches.
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Unifying Group-Relative and Self-Distillation Policy Optimization via Sample Routing

arXiv:2604.02288v1 Announce Type: cross Abstract: Reinforcement learning with verifiable rewards (RLVR) has become a standard paradigm for post-training large language models. While Group Relative Policy Optimization (GRPO) is widely adopted, its coarse credit assignment uniformly penalizes failed rollouts, lacking the token-level focus needed to efficiently address specific deviations. Self-Distillation Policy Optimization (SDPO) addresses this by providing denser, more targeted logit-level supervision that facilitates rapid early improvement, yet it frequently collapses during prolonged training. We trace this late-stage instability to two intrinsic flaws: self-distillation on already-correct samples introduces optimization ambiguity, and the self-teacher's signal reliability progressively degrades. To resolve these issues, we propose Sample-Routed Policy Optimization (SRPO), a unified on-policy framework that routes correct samples to GRPO's reward-aligned reinforcement and failed samples to SDPO's targeted logit-level correction. SRPO further incorporates an entropy-aware dynamic weighting mechanism to suppress high-entropy, unreliable distillation targets while emphasizing confident ones. Evaluated across five benchmarks and two model scales, SRPO achieves both the rapid early improvement of SDPO and the long-horizon stability of GRPO. It consistently surpasses the peak performance of both baselines, raising the five-benchmark average on Qwen3-8B by 3.4% over GRPO and 6.3% over SDPO, while simultaneously yielding moderate response lengths and lowering per-step compute cost by up to 17.2%.
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Agentified Assessment of Logical Reasoning Agents

arXiv:2603.02788v4 Announce Type: replace Abstract: We present a framework for evaluating and benchmarking logical reasoning agents when assessment itself must be reproducible, auditable, and robust to execution failures. Building on agentified assessment, we use an assessor agent to issue tasks, enforce execution budgets, parse outputs, and record structured failure types, while the agent under test only needs to expose a standardized agent-to-agent interface. As a case study, we benchmark an auto-formalization agent for first-order logic (FOL) reasoning on a solver-verified and repaired split of FOLIO. The agent translates natural language premises and conclusions into executable Z3Py programs and employs satisfiability modulo theories (SMT) solving to determine logical entailment. On the cleaned FOLIO validation set, the auto-formalization agent achieves 86.70% accuracy under the assessor protocol, outperforming a chain-of-thought baseline (73.89%).
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Labels Matter More Than Models: Rethinking the Unsupervised Paradigm in Time Series Anomaly Detection

arXiv:2511.16145v2 Announce Type: replace-cross Abstract: Time series anomaly detection (TSAD) is a critical data mining task often constrained by label scarcity. Consequently, current research predominantly focuses on Unsupervised Time-series Anomaly Detection (UTAD), relying on increasingly complex architectures to model normal data distributions. However, this algorithm-centric trend often overlooks the significant performance gains achievable from limited anomaly labels available in practical scenarios. This paper challenges the premise that algorithmic complexity is the optimal path for TSAD. Instead of proposing another intricate unsupervised model, we present a comprehensive benchmark and empirical study to rigorously compare supervised and unsupervised paradigms. To isolate the value of labels, we introduce \stand, a deliberately minimalist supervised baseline. Extensive experiments on five public datasets demonstrate that: (1) Labels matter more than models: under a limited labeling budget, simple supervised models significantly outperform complex state-of-the-art unsupervised methods; (2) Supervision yields higher returns: the performance gain from minimal supervision far exceeds the incremental gains from architectural innovations; and (3) Practicality: \stand~exhibits superior prediction consistency and anomaly localization compared to unsupervised counterparts. These findings advocate for a paradigm shift in TSAD research, urging the community to prioritize data-centric label utilization over purely algorithmic complexity. The code and benchmark are publicly available at https://github.com/EmorZz1G/STAND.
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Semantic Refinement with LLMs for Graph Representations

arXiv:2512.21106v2 Announce Type: replace-cross Abstract: Graph-structured data exhibit substantial heterogeneity in where their predictive signals originate: in some domains, node-level semantics dominate, while in others, structural patterns play a central role. This structure-semantics heterogeneity implies that no graph learning model with a fixed inductive bias can generalize optimally across diverse graph domains. However, most existing methods address this challenge from the model side by incrementally injecting new inductive biases, which remains fundamentally limited given the open-ended diversity of real-world graphs. In this work, we take a data-centric perspective and treat node semantics as a task-adaptive variable. We propose a Graph-Exemplar-guided Semantic Refinement (GES) framework for graph representation learning which -- unlike existing LLM-enhanced methods that generate node descriptions without graph context -- leverages structurally and semantically similar nodes from the graph itself to guide semantic refinement. Specifically, a GNN is first trained to produce predictive states, which along with structural and semantic similarity are used to retrieve in-graph exemplars that inform an LLM in refining node descriptions. We evaluate our approach on both text-rich and text-free graphs. Results show consistent improvements on semantics-rich and structure-dominated graphs, demonstrating the effectiveness of data-centric semantic refinement under structure-semantics heterogeneity.
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MemFactory: Unified Inference & Training Framework for Agent Memory

arXiv:2603.29493v3 Announce Type: replace-cross Abstract: Memory-augmented Large Language Models (LLMs) are essential for developing capable, long-term AI agents. Recently, applying Reinforcement Learning (RL) to optimize memory operations, such as extraction, updating, and retrieval, has emerged as a highly promising research direction. However, existing implementations remain highly fragmented and task-specific, lacking a unified infrastructure to streamline the integration, training, and evaluation of these complex pipelines. To address this gap, we present MemFactory, the first unified, highly modular training and inference framework specifically designed for memory-augmented agents. Inspired by the success of unified fine-tuning frameworks like LLaMA-Factory, MemFactory abstracts the memory lifecycle into atomic, plug-and-play components, enabling researchers to seamlessly construct custom memory agents via a "Lego-like" architecture. Furthermore, the framework natively integrates Group Relative Policy Optimization (GRPO) to fine-tune internal memory management policies driven by multi-dimensional environmental rewards. MemFactory provides out-of-the-box support for recent cutting-edge paradigms, including Memory-R1, RMM, and MemAgent. We empirically validate MemFactory on the open-source MemAgent architecture using its publicly available training and evaluation data. Across the evaluation sets, MemFactory improves performance over the corresponding base models on average, with relative gains of up to 14.8%. By providing a standardized, extensible, and easy-to-use infrastructure, MemFactory significantly lowers the barrier to entry, paving the way for future innovations in memory-driven AI agents.
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Leptomeningeal metastatic cancer cells induce a permissive choroid plexus vasculature through extracellular-vesicle-derived 5-HIAA signaling

Nature Cancer, Published online: 03 April 2026; doi:10.1038/s43018-026-01145-y

Huang, Hou, Yang et al. demonstrate that leptomeningeal metastatic cells favor the formation of a premetastatic niche by remodeling the choroid plexus vasculature through the serotonin metabolite 5-hydroxyindoleacetic acid, which signals into endothelial cells through the aryl hydrocarbon receptor.
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Correction: Integrative multi-omics and machine learning reveals the spatial niche distribution and role of CYP27A1+TAMs in immunotherapy response in non-small cell lung cancer

Front Immunol. 2026 Mar 16;17:1822612. doi: 10.3389/fimmu.2026.1822612. eCollection 2026.

ABSTRACT

[This corrects the article DOI: 10.3389/fimmu.2026.1782545.].

PMID:41918731 | PMC:PMC13033988 | DOI:10.3389/fimmu.2026.1822612

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Correction: Integrative multi-omics and machine learning reveals the spatial niche distribution and role of CYP27A1+TAMs in immunotherapy response in non-small cell lung cancer

Front Immunol. 2026 Mar 16;17:1822612. doi: 10.3389/fimmu.2026.1822612. eCollection 2026.

ABSTRACT

[This corrects the article DOI: 10.3389/fimmu.2026.1782545.].

PMID:41918731 | PMC:PMC13033988 | DOI:10.3389/fimmu.2026.1822612

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Predicting Neuromodulation Outcome for Parkinson's Disease with Generative Virtual Brain Model

arXiv:2603.29176v1 Announce Type: new Abstract: Parkinson's disease (PD) affects over ten million people worldwide. Although temporal interference (TI) and deep brain stimulation (DBS) are promising therapies, inter-individual variability limits empirical treatment selection, increasing non-negligible surgical risk and cost. Previous explorations either resort to limited statistical biomarkers that are insufficient to characterize variability, or employ AI-driven methods which is prone to overfitting and opacity. We bridge this gap with a pretraining-finetuning framework to predict outcomes directly from resting-state fMRI. Critically, a generative virtual brain foundation model, pretrained on a collective dataset (2707 subjects, 5621 sessions) to capture universal disorder patterns, was finetuned on PD cohorts receiving TI (n=51) or DBS (n=55) to yield individualized virtual brains with high fidelity to empirical functional connectivity (r=0.935). By constructing counterfactual estimations between pathological and healthy neural states within these personalized models, we predicted clinical responses (TI: AUPR=0.853; DBS: AUPR=0.915), substantially outperforming baselines. External and prospective validations (n=14, n=11) highlight the feasibility of clinical translation. Moreover, our framework provides state-dependent regional patterns linked to response, offering hypothesis-generating mechanistic insights.
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Route-Induced Density and Stability (RIDE): Controlled Intervention and Mechanism Analysis of Routing-Style Meta Prompts on LLM Internal States

arXiv:2603.29206v1 Announce Type: new Abstract: Routing is widely used to scale large language models, from Mixture-of-Experts gating to multi-model/tool selection. A common belief is that routing to a task ``expert'' activates sparser internal computation and thus yields more certain and stable outputs (the Sparsity--Certainty Hypothesis). We test this belief by injecting routing-style meta prompts as a textual proxy for routing signals in front of frozen instruction-tuned LLMs. We quantify (C1) internal density via activation sparsity, (C2) domain-keyword attention, and (C3) output stability via predictive entropy and semantic variation. On a RouterEval subset with three instruction-tuned models (Qwen3-8B, Llama-3.1-8B-Instruct, and Mistral-7B-Instruct-v0.2), meta prompts consistently densify early/middle-layer representations rather than increasing sparsity; natural-language expert instructions are often stronger than structured tags. Attention responses are heterogeneous: Qwen/Llama reduce keyword attention, while Mistral reinforces it. Finally, the densification--stability link is weak and appears only in Qwen, with near-zero correlations in Llama and Mistral. We present RIDE as a diagnostic probe for calibrating routing design and uncertainty estimation.
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iPoster: Content-Aware Layout Generation for Interactive Poster Design via Graph-Enhanced Diffusion Models

arXiv:2603.29469v1 Announce Type: cross Abstract: We present iPoster, an interactive layout generation framework that empowers users to guide content-aware poster layout design by specifying flexible constraints. iPoster enables users to specify partial intentions within the intention module, such as element categories, sizes, positions, or coarse initial drafts. Then, the generation module instantly generates refined, context-sensitive layouts that faithfully respect these constraints. iPoster employs a unified graph-enhanced diffusion architecture that supports various design tasks under user-specified constraints. These constraints are enforced through masking strategies that precisely preserve user input at every denoising step. A cross content-aware attention module aligns generated elements with salient regions of the canvas, ensuring visual coherence. Extensive experiments show that iPoster not only achieves state-of-the-art layout quality, but offers a responsive and controllable framework for poster layout design with constraints.
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MemFactory: Unified Inference & Training Framework for Agent Memory

arXiv:2603.29493v1 Announce Type: cross Abstract: Memory-augmented Large Language Models (LLMs) are essential for developing capable, long-term AI agents. Recently, applying Reinforcement Learning (RL) to optimize memory operations, such as extraction, updating, and retrieval, has emerged as a highly promising research direction. However, existing implementations remain highly fragmented and task-specific, lacking a unified infrastructure to streamline the integration, training, and evaluation of these complex pipelines. To address this gap, we present MemFactory, the first unified, highly modular training and inference framework specifically designed for memory-augmented agents. Inspired by the success of unified fine-tuning frameworks like LLaMA-Factory, MemFactory abstracts the memory lifecycle into atomic, plug-and-play components, enabling researchers to seamlessly construct custom memory agents via a "Lego-like" architecture. Furthermore, the framework natively integrates Group Relative Policy Optimization (GRPO) to fine-tune internal memory management policies driven by multi-dimensional environmental rewards. MemFactory provides out-of-the-box support for recent cutting-edge paradigms, including Memory-R1, RMM, and MemAgent. We empirically validate MemFactory on the open-source MemAgent architecture using its publicly available training and evaluation data. Across both in-domain and out-of-distribution evaluation sets, MemFactory consistently improves performance over the corresponding base models, with relative gains of up to 14.8%. By providing a standardized, extensible, and easy-to-use infrastructure, MemFactory significantly lowers the barrier to entry, paving the way for future innovations in memory-driven AI agents.
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From Efficiency to Adaptivity: A Deeper Look at Adaptive Reasoning in Large Language Models

arXiv:2511.10788v3 Announce Type: replace Abstract: Recent advances in large language models (LLMs) have made reasoning a central benchmark for evaluating intelligence. While prior surveys focus on efficiency by examining how to shorten reasoning chains or reduce computation, this view overlooks a fundamental challenge: current LLMs apply uniform reasoning strategies regardless of task complexity, generating long traces for trivial problems while failing to extend reasoning for difficult tasks. This survey reframes reasoning through the lens of {adaptivity}: the capability to allocate reasoning effort based on input characteristics such as difficulty and uncertainty. We make three contributions. First, we formalize deductive, inductive, and abductive reasoning within the LLM context, connecting these classical cognitive paradigms with their algorithmic realizations. Second, we formalize adaptive reasoning as a control-augmented policy optimization problem balancing task performance with computational cost, distinguishing learned policies from inference-time control mechanisms. Third, we propose a systematic taxonomy organizing existing methods into training-based approaches that internalize adaptivity through reinforcement learning, supervised fine-tuning, and learned controllers, and training-free approaches that achieve adaptivity through prompt conditioning, feedback-driven halting, and modular composition. This framework clarifies how different mechanisms realize adaptive reasoning in practice and enables systematic comparison across diverse strategies. We conclude by identifying open challenges in self-evaluation, meta-reasoning, and human-aligned reasoning control.
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QuestA: Expanding Reasoning Capacity in LLMs via Question Augmentation

arXiv:2507.13266v4 Announce Type: replace-cross Abstract: Reinforcement learning (RL) has emerged as a central paradigm for training large language models (LLMs) in reasoning tasks. Yet recent studies question RL's ability to incentivize reasoning capacity beyond the base model. This raises a key challenge: how can RL be adapted to solve harder reasoning problems more effectively? To address this challenge, we propose a simple yet effective strategy via Question Augmentation: introduce partial solutions during training to reduce problem difficulty and provide more informative learning signals. Our method, QuestA, when applied during RL training on math reasoning tasks, not only improves pass@1 but also pass@k-particularly on problems where standard RL struggles to make progress. This enables continual improvement over strong open-source models such as DeepScaleR and OpenMath Nemotron, further enhancing their reasoning capabilities. We achieve new state-of-the-art results on math benchmarks using 1.5B-parameter models: 72.50% (+10.73%) on AIME24, 62.29% (+12.79%) on AIME25, and 41.67% (+10.11%) on HMMT25. Code, data and model are available at https://github.com/foreverlasting1202/QuestA.
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