Ouabain triggers cochlear spiral ganglion neuron (SGN) ferroptosis and hearing loss via SCD1 downregulation. MITF directly activates Scd1 transcription, and the MITF–SCD1 axis mitigates SGN ferroptosis and hearing impairment in ototoxic ouabain and cisplatin models, revealing a lipid metabolic vulnerability and therapeutic target for sensorineural hearing loss.

npj Digital Medicine, Published online: 24 March 2026; doi:10.1038/s41746-026-02424-9

Evaluating eRAMP telecare for diabetes in outpatient clinics: a hybrid effectiveness-implementation study