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AgentSLR: Automating Systematic Literature Reviews in Epidemiology with Agentic AI

arXiv:2603.22327v1 Announce Type: cross Abstract: Systematic literature reviews are essential for synthesizing scientific evidence but are costly, difficult to scale and time-intensive, creating bottlenecks for evidence-based policy. We study whether large language models can automate the complete systematic review workflow, from article retrieval, article screening, data extraction to report synthesis. Applied to epidemiological reviews of nine WHO-designated priority pathogens and validated against expert-curated ground truth, our open-source agentic pipeline (AgentSLR) achieves performance comparable to human researchers while reducing review time from approximately 7 weeks to 20 hours (a 58x speed-up). Our comparison of five frontier models reveals that performance on SLR is driven less by model size or inference cost than by each model's distinctive capabilities. Through human-in-the-loop validation, we identify key failure modes. Our results demonstrate that agentic AI can substantially accelerate scientific evidence synthesis in specialised domains.
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Do Large Language Models Reduce Research Novelty? Evidence from Information Systems Journals

arXiv:2603.22510v1 Announce Type: cross Abstract: Large language models such as ChatGPT have increased scholarly output, but whether this productivity boost produces genuine intellectual advancement remains untested. I address this gap by measuring the semantic novelty of 13,847 articles published between 2020 and 2025 in 44 Information Systems journals. Using SPECTER2 embeddings, I operationalize novelty as the cosine distance between each paper and its nearest prior neighbors. A difference-in-differences design with the November 2022 release of ChatGPT as the treatment break reveals a heterogeneous pattern: authors affiliated with institutions in non-English-dominant countries show a 0.18 standard deviation decline in relative novelty compared to authors in English-dominant countries (beta = -0.176, p
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