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Dominant clones leverage developmental epigenomic states to drive ependymoma

βœ‡Nature - Issue - nature.com science feeds
By: Alisha S. Kardian Β· Hua Sun Β· Siri Ippagunta Β· Nicholas Laboe Β· Srinidhi Varadharajan Β· Kwanha Yu Β· Hsiao-Chi Chen Β· Erik Emanus Β· Tuyu Zheng Β· Riley M. Deneen Β· Jon P. Connelly Β· Yong-Dong Wang Β· Jiangshan Zhan Β· Hengxi Liu Β· Kimberley Lowe Β· Taylor Bugbee Β· Rakesh Pathak Β· Amanda Bland Β· Sanya Mehta Β· Sophie Cochiolo Β· Amir Arabzade Β· Blake Holcomb Β· Kaitlin M. Budd Β· Gabriele Kembuan Β· Tristen Wright Β· Emma Caesar Β· Maxwell Park Β· Amelia Hancock Β· David Gee Β· Joel Murdoch Β· Yi Xiao Β· Samuel K. McBrayer Β· Thomas E. Merchant Β· Jun Qi Β· Adam D. Durbin Β· Lindsay A. Schwarz Β· Li Wang Β· Andrew M. Donson Β· Nicholas K. Foreman Β· Sameer Agnihotri Β· Alfonso Lavado Β· Suzanne J. Baker Β· David W. Ellison Β· Hyun Kyoung Lee Β· Shondra M. Pruett-Miller Β· Kelsey C. Bertrand Β· Benjamin Deneen Β· Stephen C. Mack

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10270-8

Single-nucleus chromatin and RNA sequencing identifies epigenetic chromatin domains that confer vulnerability to paediatric brain tumours such as ependymomas, providing insight into the development of such tumours despite β€˜quiet’ genomes.
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Evaluating eRAMP telecare for diabetes in outpatient clinics: a hybrid effectiveness-implementation study

βœ‡npj Digital Medicine
By: Arkers Kwan Ching Wong Β· Ssu-Chi Chen Β· Frances Kam Yuet Wong Β· Jun Liang Β· Danny Wah Kun Tong Β· Luna Ziqi Liu Β· Man Li Chan Β· Man Kin Wong Β· Bo Chu Wong Β· Vivian Hui Β· Cecilia Yeuk Sze Tang Β· Wai Hing Ho Β· Sau Ching Chiang

npj Digital Medicine, Published online: 24 March 2026; doi:10.1038/s41746-026-02424-9

Evaluating eRAMP telecare for diabetes in outpatient clinics: a hybrid effectiveness-implementation study
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TRIM21-mediated degradation of HILPDA overcomes anti-PD-1 immunotherapy resistance in breast cancer by limiting PD-L1 palmitoylation

βœ‡Oncogene - Issue - nature.com science feeds
By: Xi Wang Β· Guangyan Li Β· Jiaming Wu Β· Baiyang Fu Β· Haoyang Zhang Β· Yichi Chen Β· Jianjiao Wang Β· Jianguo Zhang Β· Xi Chen

Oncogene, Published online: 24 March 2026; doi:10.1038/s41388-026-03728-6

TRIM21-mediated degradation of HILPDA overcomes anti-PD-1 immunotherapy resistance in breast cancer by limiting PD-L1 palmitoylation
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