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FigAgent: Towards Automatic Method Illustration Figure Generation for AI Scientific Papers

arXiv:2603.29590v1 Announce Type: cross Abstract: Method illustration figures (MIFs) play a crucial role in conveying the core ideas of scientific papers, yet their generation remains a labor-intensive process. In this paper, we identify three key characteristics that substantially influence MIF generation quality, i.e., \emph{compositional complexity}, \emph{component similarity}, and \emph{design dynamics}. To handle these characteristics, we take inspiration from human authors' drawing practices and propose \textbf{FigAgent}, a novel multi-agent framework for automatically generating high-quality MIFs. Through multi-agent collaboration, our FigAgent distills drawing experiences across similar components of MIFs and encapsulates them into reusable tools that can be invoked during MIF generation, while evolving these tools to adapt to dynamic design requirements. Besides, a novel Explore-and-Select drawing strategy is introduced to mimic the human-like trial-and-error manner for gradually constructing MIFs with complex structures. Extensive experiments show the efficacy of our method. Project is available \href{https://zhuolingli.github.io/FigAgent-page-project/}{here}.
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Mechanisms Underlying Drought Adaptability in Duolang Sheep Based on Metabolomic and Transcriptomic Analyses

Biology (Basel). 2026 Mar 12;15(6):461. doi: 10.3390/biology15060461.

ABSTRACT

This study investigates the mechanisms underlying drought adaptability in Duolang sheep, a local breed from two distinct habitats in Xinjiang-an arid southern region and a grassland northern region-aiming to identify key factors driving differential environmental adaptation. Integrated multi-omics analyses were performed, including serum biochemical assays, untargeted metabolomics of perirenal and tail fat tissues, and transcriptomic profiling of lung, liver, and kidney samples. Our results revealed notable differences: (1) serum levels of GSH-Px, IL-2, and IgG were significantly higher in the southern group (p < 0.01); (2) metabolomic analysis identified key differential metabolites, including EPA (involved in unsaturated fatty acid biosynthesis), choline (glycerophospholipid metabolism), L-serine and glutathione (cofactor biosynthesis), and taurine (sulfur metabolism); and (3) transcriptomic analysis revealed significant differential expression of genes such as FGF21 (thermogenesis), CD14 and DUSP2 (MAPK signaling pathway), GOT1 (arginine biosynthesis), and AVPR2 (vasopressin-regulated water reabsorption). Integrative correlation analysis further indicated that glutathione, EPA, GOT1, and CD14 are involved in energy and lipid metabolism, while taurine, AVPR2, and DUSP2 contribute to oxidative stress resistance and immune regulation. These molecular and metabolic adjustments collectively enhance drought adaptability in southern Xinjiang Duolang sheep. In conclusion, adaptation to arid environments requires enhanced antioxidant capacity and immune function, with metabolites such as EPA supporting lipid metabolism and genes such as FGF21 regulating fatty acid oxidation to limit triglyceride accumulation.

PMID:41892221 | PMC:PMC13023672 | DOI:10.3390/biology15060461

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