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Deconstruction of a spino-brain–spinal cord circuit that drives chronic pain

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10296-y

In mice, a circuit between the spinal cord and various regions of the brain, centring on spinal-cord-projecting neurons in the rostral ventromedial medulla, has a key role in driving chronic pain.
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A unified deep learning framework for cross-platform harmonization of multi-tracer PET quantification in neurodegenerative disease

npj Digital Medicine, Published online: 30 March 2026; doi:10.1038/s41746-026-02570-0

A unified deep learning framework for cross-platform harmonization of multi-tracer PET quantification in neurodegenerative disease
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