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Strand-asymmetric G-runs and G4s downstream of TSS modulate tumor suppressor gene transcription

Oncogene - Issue - nature.com science feeds

By: Dan Huang · Xiaoting Zhang · Xiansong Wang · Ziheng Huang · Judeng Zeng · Xiaodong Liu · Likai Tan · Lin Zhang · Zhenxing Guo · Tony Gin · Jun Yu · Kwok M. Ho · Matthew Tak Vai Chan · Huarong Chen · William Ka Kei Wu

2 April 2026 at 08:00

Oncogene, Published online: 02 April 2026; doi:10.1038/s41388-026-03761-5

Strand-asymmetric G-runs and G4s downstream of TSS modulate tumor suppressor gene transcription

Pyruvate is a natural suppressor of interferon signaling by inducing STAT1 protein pyruvylation

Cell

By: Yibo Zuo · Qin Wang · Wanying Tian · Xinhe Wang · Zhijin Zheng · Wei He · Renxia Zhang · Qian Zhao · Ying Miao · Yukang Yuan · Tingting Zhang · Qun Cui · Yuerong Zhang · Chunyan Liu · Haiyan Zhou · Hui Zheng

27 February 2026 at 08:00

Yibo et al. identify protein pyruvylation as a post-translational modification that can modulate immune signaling and host antiviral response.