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HERC1 oncogene enhances stemness and tumorigenic potential in CD44<sup>+</sup>-derived organoids of head and neck squamous cell carcinoma through IL-6/STAT3 signaling

βœ‡Oncogene - Issue - nature.com science feeds
By: Eunjin Jeong Β· Hye Lin Kim Β· Seohee Park Β· Seojin Jang Β· Jamin Ku Β· Hajeong Kim Β· Haeun Kim Β· Seo Lyn Choi Β· Kang Pa Lee Β· Suji Baek Β· Jeong-Yoon Yang Β· Jung Ho Park Β· Jangok Yeo Β· Jae Jun Lee Β· Sei Young Lee Β· Seok-Hyung Kim Β· Hong Sook Kim Β· Chang-Whan Yoon Β· Sang-Hyuk Lee

Oncogene, Published online: 11 April 2026; doi:10.1038/s41388-026-03725-9

HERC1 oncogene enhances stemness and tumorigenic potential in CD44+-derived organoids of head and neck squamous cell carcinoma through IL-6/STAT3 signaling
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Engineered immunosuppressive dendritic cells protect against cardiac remodelling

βœ‡Nature - Issue - nature.com science feeds
By: Xiaoying Li Β· Jiamin Li Β· Guohua Li Β· Lisheng Zhu Β· Guo Cheng Β· Huanqiang Li Β· Hao Lin Β· Ningqing Jia Β· Xiaoqian Hong Β· Ye Liu Β· Zhiwei Zhong Β· Yize Chen Β· Biqing Wang Β· Jing Zhao Β· Zhenqi Hua Β· Lingjun Wang Β· Qiming Chen Β· Peijie Zheng Β· Shuyuan Sheng Β· Songting Gu Β· Cheng Ni Β· Shuchang Ye Β· Changle Ke Β· Feimu Zhang Β· Mo Li Β· Shaohui Shi Β· Junhua He Β· Yan Wu Β· Yinghui Xu Β· Minjian Kong Β· Qi Chen Β· Huajun Li Β· Yu Zhang Β· Jianzhong Sun Β· Guanhua Hu Β· Chengchen Zhao Β· Yiping Dong Β· Lili Yu Β· Yang Xu Β· Xinyang Hu

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10346-5

Lesion-targeted immune modulation is a feasible strategy to control cardiac fibrosis, and engineered dendritic cells are a promising therapeutic platform for treating cardiac remodelling and heart failure.
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