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GPX8<sup>+</sup> cancer-associated fibroblast-derived lactate contributes to lenvatinib resistance by facilitating BRPF1 expression through histone H3 lysine 18 lactylation in hepatocellular carcinoma

βœ‡Oncogene - Issue - nature.com science feeds
By: Qinsi Wan Β· Jie Li Β· Mengzhou Guo Β· Jiahao Hu Β· Liangliang Bai Β· Meixia Zhang Β· Bimin Li Β· Yuan Fang Β· Xiaojing Du Β· Xingxing Zhang Β· Li Song Β· Sinuo Chen Β· Zhuoran Qi Β· Jinglin Xia Β· Bei Lv Β· Mingyan He

Oncogene, Published online: 22 May 2026; doi:10.1038/s41388-026-03711-1

GPX8+ cancer-associated fibroblast-derived lactate contributes to lenvatinib resistance by facilitating BRPF1 expression through histone H3 lysine 18 lactylation in hepatocellular carcinoma
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A pathogen lncRNA secreted into rice sequesters a host miRNA for virulence

βœ‡Nature - Issue - nature.com science feeds
By: Min He Β· Jia Su Β· Xiaogang Zhou Β· Tuo Qi Β· Jiazheng Wang Β· Tianxin Zhang Β· Jinhua Chen Β· Mawsheng Chern Β· Youpin Xu Β· Xiang Lu Β· Qingqing Hou Β· Hongrui Liu Β· Wenfang Huang Β· Jiawei Liu Β· Shiying Li Β· Yunfei Zhu Β· Xue Chen Β· Senyu Ran Β· Han Li Β· Renju Liu Β· Mingliang Lei Β· Guosong Shu Β· Haicheng Liao Β· Junjie Yin Β· Xiaobo Zhu Β· Yongyan Tang Β· Li Song Β· Long Wang Β· Qing Xiong Β· Jiali Liu Β· Yu Bi Β· Yihua Yang Β· Hai Qing Β· Bingtian Ma Β· Yan Li Β· Jing Fan Β· Peng Qin Β· Yuping Wang Β· Jianming Wu Β· Wenming Wang Β· Shigui Li Β· Weitao Li Β· Jing Wang Β· Xuewei Chen

Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10572-x

A fungal long non-coding RNA from Magnaporthe oryzae translocates into rice cells to sequester a host microRNA that normally represses PKR1, a negative immunity regulator, thereby facilitating infection and revealing a widespread RNA-based pathogen–host interaction mechanism.
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