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On the Stability and Realizability of Recurrent Polynomial Surrogate Ternary Logic Gate Networks

arXiv:2605.24649v1 Announce Type: cross Abstract: Recurrent Neural Networks (RNNs) can learn to predict Signal Temporal Logic (STL) verdicts online from partial trajectories, but deploying them as runtime monitors in safety-critical systems demands more than predictive accuracy. Standard RNN architectures offer no structural guarantee that outputs degrade gracefully under sensor degradation; a dropped input can silently flip a verdict from safe to unsafe. We introduce the Recurrent Differentiable Ternary Logic Gate Network (R-DTLGN), a recurrent architecture that operates over Kleene's three-valued logic $\{-1, 0, +1\}$, where $0$ explicitly represents unknown. The R-DTLGN trains through continuous polynomial surrogates and hardens to a discrete ternary logic circuit at inference. We analyze the hardened circuit through two gate vocabularies derived from two orderings on the ternary domain: numerically monotone gates ensure stable recurrent dynamics, while information-monotone gates, when present, guarantee principled abstention (unknown inputs never produce wrong outputs) and monotonicity in input certainty (more information can only improve the verdict). We show that the recurrent connections required by bounded STL operators use exclusively AND and OR, which belong to both vocabularies, linking the monitoring task to the architecture's guarantees. A realizability bound derived from the STL formula's temporal operators directly sizes the network's hidden state, replacing hyperparameter search with a formula-driven specification. We evaluate on STL specifications over D4RL PointMaze navigation data, testing prediction accuracy, degradation under predicate dropout, and the accuracy-versus-safety tradeoff between two label construction pipelines. The R-DTLGN is, to our knowledge, the first recurrent architecture that couples learned temporal prediction with formal degradation guarantees rooted in three-valued logic.
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ClaimDiff-RL: Fine-Grained Caption Reinforcement Learning through Visual Claim Comparison

arXiv:2605.20278v2 Announce Type: replace-cross Abstract: Long-form image captioning exposes a reward granularity problem in RL: captions are judged as whole sequences, while the important errors occur at the level of individual visual claims. A good dense caption should be both faithful and informative, avoiding hallucination without omitting salient details. Yet pairwise preferences, reference-based metrics, and holistic scalar rewards compress these local errors into a single sequence-level signal, obscuring the tradeoff between factuality and coverage. We introduce ClaimDiff-RL, a framework that uses reference-conditioned atomic claim differences as the reward unit for caption RL. Given an image, an actor caption, and a reference caption, a multimodal judge enumerates visually grounded differences, verifies each difference against the image, assigns open-vocabulary error types and severity levels, and produces per-difference statistics for reward composition. This makes hallucinated claims and omitted salient facts separately measurable and tunable. Experiments show that holistic scalar rewards can reduce hallucination by increasing missing facts, while ClaimDiff-RL exposes this faithfulness and coverage tradeoff and enables more balanced operating points. On a 160-image human-labeled diagnostic benchmark, public captioning benchmarks, and VQA benchmarks, ClaimDiff-RL improves the hallucination--missing-fact balance, preserves general capability, and even surpasses Gemini-3-Pro-Preview on several fine-grained Capability dimensions such as object counting, spatial relations, and scene recognition. These results suggest that typed, verifiable claim differences are an effective reward unit for fine-grained and diagnosable caption RL.
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circPARPBP promotes cancer stemness and chemoresistance in triple-negative breast cancer through recruiting SRCAP complex to activate CCL20 transcription

Oncogene, Published online: 21 May 2026; doi:10.1038/s41388-026-03819-4

circPARPBP promotes cancer stemness and chemoresistance in triple-negative breast cancer through recruiting SRCAP complex to activate CCL20 transcription
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Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis

Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03797-7

Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis
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