Jin and colleagues review recent advances in mRNA vaccines for infectious diseases and cancer, covering sequence optimization, circRNA/saRNA platforms, delivery systems, and clinical translation challenges, while highlighting the role of computational technologies.

Nature Cancer, Published online: 01 September 2026; doi:10.1038/s43018-026-01220-4

Chen et al. have developed SlideChat, a multimodal generative artificial intelligence assistant, which they benchmark on 27 pathology tasks across 33 cancer types. Expert pathologists rated the assistant as clinically relevant and accurate.